Method to increase carotenoid production in a microbial host...

Details Method to increase carotenoid production in a microbial host... Method to increase carotenoid production in a microbial host...

2007-05-15

2007-05-15

Kerr, Kathleen M. (Department: 1656)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

C435S067000, C435S471000, C435S063000

Reexamination Certificate

active

11227613

ABSTRACT:
A method to increase carotenoid production in carotenogenic microbial host cells is provided by down-regulating or disrupting glycogen synthesis. Disruption of glycogen synthase activity in a carotenogenic microbial host cell significantly increased carotenoid production. Carotenogenic microorganisms are also provided that have been optimized for the production of carotenoid compounds through the down-regulation and/or disruption of glycogen synthase activity.

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