Method to fabricate inhomogeneous particles

Details Method to fabricate inhomogeneous particles Method to fabricate inhomogeneous particles

2011-08-30

2011-08-30

Kiliman, Leszek (Department: 1788)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Particulate form

C424S490000, C264S004000, C427S212000, C428S403000, C428S404000, C428S407000

Reexamination Certificate

active

08007829

ABSTRACT:
A method for making inhomogeneous microparticles comprises a) providing an amount of each of at least two polyelectrolytes having a charge, b) providing an amount of a counterion having a valence of at least 2, c) combining the polyelectrolytes and the counterion in a solution such that the polyelectrolyte self-assembles to form inhomogeneous aggregates, and d) adding nanoparticles to the solution such that nanoparticles arrange themselves around the inhomogeneous aggregates to form inhomogeneous particles. The polyelectrolyte may have a positive or negative charge. The charge ratio R of total charge of the counterions to the total charge of the polyelectrolyte may be greater than 1.0.

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