Method to fabricate a chip for the detection of biological...

Semiconductor device manufacturing: process – Having biomaterial component or integrated with living organism

Reexamination Certificate

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C257SE21409, C438S049000, C438S142000

Reexamination Certificate

active

07927888

ABSTRACT:
Improved method to fabricate a microelectronic device provided with at least one circuit to detect biological elements, comprising the steps of:a) forming transistors,depositing at least one layer in at least one insulating material (141) coating said transistors,forming one or more holes (143) in said layer of insulating material (141), so as to expose the upper face of the respective gate (135) of first-type transistors,filling the holes with a gate material,b) removing, at least in part, the respective gate (135) of the first-type transistors, whilst the gate of second-type transistors is protected, the method prior to or at the same time as said removal conducted at step b) further comprising the removal of said gate material.

REFERENCES:
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patent: 102 55 755 (2004-07-01), None
patent: 1 557 884 (2005-07-01), None
Andreas Hierlemann, et al., “Microfabrication Techniques for Chemical/Biosensors”, Proceedings of the IEEE, vol. 91, No. 6, Jun. 1, 2003, XP-011097409, pp. 839-863.
Fernando Patolsky, et al., “Fabrication of silicon nanowire devices for ultrasensitive, label-free, real-time detection of biological and chemical species”, Nature Protocols, vol. 1, No. 4, 2006, pp. 1711-1724.
Yuri L. Bunimovich, et al., “Quantitative Real-Time Measurements of DNA Hybridization with Alkylated Nonoxidized Silicon Nanowires in Electrolyte Solution”, Journal of American Chemical Society, 128, 2006, pp. 16323-16331.
Eric Stern, et al., “Label-free immunodetection with CMOS-compatible semiconducting nanowires”, Nature, vol. 445, Feb. 2007, pp. 519-522.

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