Method to deliver compositions conferring resistance to alopecia

Details Method to deliver compositions conferring resistance to alopecia Method to deliver compositions conferring resistance to alopecia

1995-06-07

1998-05-19

Elliott, George C.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Liposomes

424 701, 514 2, 514 44, A61K 9127, A61K 706, A61K 3170, A61K 3800

Patent

active

057532630

ABSTRACT:
The invention describes a method to deliver a composition selectively to hair follicles using a liposomal formulation. Proteins which are cell cycle inhibitors are products of the multi-drug resistance gene or the recombinant materials for their production are targeted to hair follicles by encapsulating them in liposomes.

REFERENCES:
patent: 4755388 (1988-07-01), Heath et al.
patent: 4919664 (1990-04-01), Oliver et al.
patent: 4925661 (1990-05-01), Huang
patent: 4957735 (1990-09-01), Huang
patent: 5077211 (1991-12-01), Yarosh
patent: 5190762 (1993-03-01), Yarosh
patent: 5223263 (1993-06-01), Hostetler et al.
patent: 5618798 (1997-04-01), Bar-Shalom et al.
Jiminez et al. (1992) Treatment with ImuVert/N-acetylcysteine protects rats from cyclophosphamide/cytarabine-induced alopecia. Cancer Invest. 10:271-276.
Hoffman, R.M. et al., "Letter to the Editor: Liposomes can Specifically Target Entrapped Melanin to Hair Follicles in Histocultured Skin," In Vitro Cell. Dev. Biol. (Mar. 1993) 29A: 192-194.
Gregoriadis, G. "Liposomes for drugs and vaccines," Trends in Biotechnology(1985) 3(9):235-241.
Maibach, H.I. et al., "Regional Variation in Percutaneous Penetration in Man," Arch. Environ. Health 23 (Sep. 1971):208-211.
Hoffman, R.M. et al. "Binding and Entrapment of High Molecular Weight DNA by Lecithin Liposomes," FEBS Letters (Sep. 1978) 98(2):365-368.
Lieb, L.M. et al. "Topical Delivery Enhancement with Multilamellar Liposomes into Pilosebaceous Units: I. In Vitro Evaluation Using Fluorescent Techniques with the Hamster Ear Model," Journal of Investigative Dermatology (Jul. 1992) 99(1):108-113.
Li et al., "Liposomes Can Specifically Target Entrapped Melanin to Hair Follicles in Histocultured Skin," In Vitro Cellular & Developmental Biology, (Mar. 1993) 29A, No. 3, Part I:192-194.
H.H. Schmidt, ed., Liposomes as drug carriers, Stuttgart: George Thieme Verlag (1986).

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