Chemistry: molecular biology and microbiology – Vector – per se
Reexamination Certificate
2004-02-09
2010-10-05
Lucas, Zachariah (Department: 1648)
Chemistry: molecular biology and microbiology
Vector, per se
C435S005000, C435S006120, C536S023720
Reexamination Certificate
active
07807455
ABSTRACT:
The present invention features methods for producing HCV replicons using HCV encoding sequences from different isolates. The featured methods are based on the discovered importance of NS3 amino acid position 470 in conferring cell culture replication activity to different HCV isolates.
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Flores Osvaldo
Grobler Jay
Markel Eric J.
Heber Sheldon O.
Lucas Zachariah
Merck Sharp & Dohme Corp.
Wenk Melissa B.
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