Electricity: measuring and testing – Of geophysical surface or subsurface in situ – For small object detection or location
Reexamination Certificate
2001-07-18
2003-04-01
Lefkowitz, Edward (Department: 2862)
Electricity: measuring and testing
Of geophysical surface or subsurface in situ
For small object detection or location
C324S441000
Reexamination Certificate
active
06541978
ABSTRACT:
The present invention relates to a method, a system and a device for producing signals from a substance, in particular electric signals, characteristic of the biological and/or chemical activity or the biological and/or chemical behaviour of said substance or an active element contained in said substance. The invention also relates to a method and a system for controlling said signals. The invention also relates to the applications of said method, system and device in particular to the production of active substances and to the detection of defined substances. Finally, the invention relates to signals linked to a biological and/or chemical activity thus produced by said method, system and device.
It is known from the research works of Jacques Benveniste, in particular those described in the patent application WO 94/17406 published on Aug. 4, 1994, that one can pick up, from a biological and/or chemical active element such as a chemical compound, a cell or a micro-organism, or from a substance containing this active element such as a purified preparation, a biological sample, or a living being, an “electromagnetic signal characteristic of the biological and/or chemical activity or of the biological and/or chemical behaviour” of said substance and/or said active element contained in said substance.
It is also known that it is possible to transform, in particular by means of a transducer, such an electromagnetic signal into electric signals. In the following text one also means by “electric signals characteristic of the biological and/or chemical activity or of the biological and/or chemical behaviour of said substance or of an active element contained in said substance” the electric signals derived by signal digitising and/or processing. In this expression the word “characteristic” is used in the meaning where the physical parameters of the electric signals are specific to the substance or to the active element contained in said substance and that the application of these electric signals, via a transducer, to a biological control system makes it possible:
(i) to induce a biological and/or chemical activity on said biological control system relative to that of the substance of origin or the active element it contains;
(ii) to reveal a characteristic of the substance or the active element it contains, at the origin of said electric signals.
The patent application WO 94/17406 published on Aug. 4, 1994, describes a method and a device for picking up “an electromagnetic signal characteristic of a biological and/or chemical activity or of a biological and/or chemical behaviour” from a biological and/or chemical active element such as a chemical compound, a cell or micro-organism, o r from a substance containing this active element such as a purified preparation, a biological sample, or a living being.
Since then the inventors have discovered that it is possible to improve the quality of the electromagnetic signal picked up as well as the reliability of the method for producing these signals and that consequently it is possible to produce characteristic electric signals appropriate for industrial applications. The production of such characteristic electric signals implies an exceptional industrial importance.
It thus becomes possible to detect and characterise active elements present in low concentration or in very low concentration in a substance. As examples, it is thus possible to monitor the presence or absence of chemical compounds such as caffeine, ionophoretic-calcium, ovalbumin, propranolol or micro-organisms such as bacterium coli, streptococci, staphilocci whose presence is looked for.
It thus becomes possible to carry out remote tests at several thousands of kilometers since the characteristic signals are electric signals which can immediately be transmitted to the investigation centre of the control laboratory.
It is possible to modify the biological and/or chemical activity or the biological and/or chemical behaviour of a biological receptor system by submitting it to the effects of characteristic electric signals. It also becomes possible to produce new drugs such as solutions depending on signals from arnica, bradykinin, caffeine, nicotine. New production techniques for drugs can be implemented. For example, in the case of certain drugs such as antibiotics, anti-viruses, anti-parasites, anti-mitotics which, to act within bacteria, viruses or cells (tumour cells in particular), must breach the defensive barriers of the above, the signals of these drugs are applied directly into the heart of the bacteria, viruses or cells. In fact, the application of characteristic electric signals, via a n appropriate transducer, generates magnetic fields which penetrate into the bacteria, viruses or cells and modify their chemical and/or biological behaviour.
It is possible to store the characteristic electric signals in data banks, using computer techniques. Then, the spread of therapeutic resources, from one point to the other on the planet, is instantaneous according to needs.
The examples described above concern the medical domain. The chemical industry also, such as electronic components, will also be concerned by the new possibilities offered by the present invention. The use of electromagnetic fields, emitted by characteristic electric signals, to modify the behaviour of molecules and promote chemical reactions will open up new prospects concerning both the conception of new materials and their methods of production. Thus, for example, it will be possible to use them as catalysts able to influence the stereochemistry of molecules.
The method according to the invention making it possible to improve the performances of characteristic electric signals comprises the stages:
of placing said substance in a zone submitted to a specific excitation field of electric, magnetic and/or electromagnetic nature,
of transforming the fields resulting from the interaction of the specific excitation field and the substance, into signals, in particular electric signals, by means of a first transducer receiving said resulting fields.
In fact, the inventors have noted that, in a surprising manner, the use of an excitation field such as for example an electromagnetic field of uniform power spectral density over a frequency spread (for example white noise of 1 Hz to 20 kHz) makes it possible to improve the performance of characteristic electric signals. As an example of such a first transducer, one can mention very sensitive small copper wire bobbins with an impedance of 300 Ohms; internal diameter of 6 mm, external diameter of 16 mm, length 6 mm, normally used as telephone receivers.
Preferably, the process according to the invention further comprises the stage for processing said signals derived from said first transducer, relative to second signals derived from a second transducer receiving the specific excitation field, in the absence of said substance. As an example, the processing can consist of subtracting these two signals by using two receiver bobbins connected in series and with opposite phases, one facing said substance and receiving the electromagnetic field through said substance and the other receiving the electromagnetic field directly. Thus, the part of the signals really characteristic of the biological and/or chemical activity or of the biological and/or chemical behaviour of said substance or said active element contained in said substance, is enhanced relative to that derived from the first transducer alone.
As an example, according to another embodiment of the invention, the processing can consist of recording consecutively the signals coming from said substance and then the signals coming from a neutral substance (water or physiological serum), then subtracting the first signals from the second (which serve as reference), this subtraction being carried out before or after processing the signals as described below (subtraction of amplitudes or power spectral densities).
Preferably, according to another embodiment of the invention, the process according to the invention comprises th
Benveniste Jacques
Guillonnet Didier
Digibio
Lefkowitz Edward
Zaveri Subhash A
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