Method separating phenylalanine and cinnamic acid

Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acids and salts thereof

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C07C 9912

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046044833

ABSTRACT:
In a method of separating phenylalanine and cinnamic acid from a mixed solution containing phenylalanine and cinnamic acid, a method of separating phenylalanine and cinnamic acid which comprises subjecting said mixed solution to chromatographic development using a synthetic adsorbent, such as Diaion, Amberlite etc., in the presence of a salt, such as ammonium halides, ammonium sulfate, alkali metal nitrates, ammonium and alkali metal salts of fatty acids, at a concentration in the range where the salting-out effect on cinnamic acid is greater than that on phenylalanine and also both phenylalanine and cinnamic acid can be dissolved, for example, in the range of 0.2-5N.

REFERENCES:
Samejima, The Microbial Production of Amino Acids, pp. 227-259 (1972).

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