Method of viral chemoprophylaxis and compounds therefor

Details Method of viral chemoprophylaxis and compounds therefor Method of viral chemoprophylaxis and compounds therefor

1975-06-26

1977-05-31

Drezin, Norman A.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Recombinant or stably-transformed bacterium encoding one or...

424249, 424269, A61K 31155

Patent

active

040270394

ABSTRACT:
It has been found that compounds having a stereochemically unencumbered access to a nitrogen-nitrogen bond have antiviral activity in extremely low dose ranges. Hydrazine, hydrazine derivatives and related compounds have been found to be active in protecting animals against disease caused by both DNA and RNA type viruses at doses of about 250 picograms to 250 micrograms per kilogram of host body weight.

REFERENCES:
patent: 3429966 (1969-02-01), Gall et al.
patent: 3436461 (1969-04-01), Scotti et al.
patent: 3576844 (1971-04-01), Ishida et al.
patent: 3855242 (1974-12-01), Chapman et al.
Chemical Abstracts 62:15264 c, (1965).
Chemical Abstracts 56:4047 b, (1961).
Chemical Abstracts 62:8139 d, (1965).
Chemical Abstracts 57:17191 f, (1962).

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