Chemistry: analytical and immunological testing – Automated chemical analysis – With aspirator of claimed structure
Patent
1997-12-05
2000-05-09
Le, Long V.
Chemistry: analytical and immunological testing
Automated chemical analysis
With aspirator of claimed structure
436 50, 436180, 422 67, 422 81, 422100, 7386401, 7386415, G01N 3510
Patent
active
060603208
ABSTRACT:
A nethod of verifying sample volume quantifies the fluid volume aspirated and verifies sample uniformity by detecting the presence of foam or clots in the sample. After aspiration, a pressure sensor is used to measure the vacuum needed to hold up the column of fluid in the probe tip. By knowing the geometry of the probe tip, the vacuum can be converted to a sample weight and volume, based on sample densities. Non-ideal conditions, such as foam on the surface of the fluid or a clot in the fluid, result in a sample volume much lighter in the case if foam, or much greater, in the case of a clot, than anticipated. The method also determines the elapsed time of the aspiration. Foamy samples result in aspiration times shorter than normal. Clotted samples result in aspiration times longer than normal.
REFERENCES:
patent: 5013529 (1991-05-01), Itoh
patent: 5452619 (1995-09-01), Kawanabe et al.
patent: 5463895 (1995-11-01), Brentz
patent: 5488854 (1996-02-01), Kawanabe et al.
patent: 5488874 (1996-02-01), Kawanabe et al.
patent: 5537880 (1996-07-01), Takeda et al.
patent: 5540081 (1996-07-01), Takeda et al.
patent: 5723795 (1998-03-01), Merriam
Omar S. Khalil et al., "Abbott Prism: A Multichannel Heterogeneous Chemiluminescence Immunoassay Analyzer" Clin. Chem. 37/9, pp. 1540-1547 (1991).
Dorenkott Jeffrey S.
Panek Carl F.
Bayer Corporation
Gagnebin , III Charles L.
Le Long V.
Moriarty Gordon
LandOfFree
Method of verifying aspirated volume in automatic diagnostic sys does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method of verifying aspirated volume in automatic diagnostic sys, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of verifying aspirated volume in automatic diagnostic sys will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1064104