Method of vaccination for prevention of Bordetella bronchiseptic

Details Method of vaccination for prevention of Bordetella bronchiseptic Method of vaccination for prevention of Bordetella bronchiseptic

1981-09-21

1985-07-23

Rose, Shep K.

Drug, bio-affecting and body treating compositions

Whole live micro-organism, cell, or virus containing

Genetically modified micro-organism, cell, or virus

206510, A61K 3910

Patent

active

045308322

ABSTRACT:
Viable cells of an avirulent self-clearing strain of B. bronchiseptica are administered as an intra-respiratory vaccine. An aqueous suspension of the cells is applied to the respiratory mucosa immediately after incorporating a non-inhibitory amount of a wetting agent promoting the mucosal implantation of the cells. Effective immunization can thereby be obtained against diseases such as kennel cough in dogs and atrophic rhinitis in swine even through the strain of B. bronchiseptica is so highly attenuated that it is self-clearing from the respiratory mucosa.

REFERENCES:
patent: 3384544 (1968-05-01), Walton et al.
patent: 3567585 (1971-03-01), Bloch et al.
patent: 3607858 (1971-09-01), Querry et al.
patent: 4225583 (1980-09-01), Switzer et al.

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