Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2006-08-29
2006-08-29
Brumback, Brenda (Department: 1647)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C435S007210
Reexamination Certificate
active
07097984
ABSTRACT:
Methods and kits are provided for manipulating and predicting the reproductive capacity of a female subject. The presence of endogenous neurotrophins and addition of exogenous neurotrophins, particularly BDNF, NT-4/5, and NGF, increase the reproductive capacity of a female patient by binding to receptors on the oocytes and stimulating maturation of the oocytes. Administration of antagonists act as a contraceptive because the antagonists prevent the neurotrophins from binding to oocyte receptors. Neurotrophins may also be used to stimulate the maturation of oocyte in vitro.
REFERENCES:
patent: WO 93/25684 (1993-06-01), None
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Dreyfus Cheryl
Feng Bo
Seifer David B
Shelden Robert
Brumback Brenda
Licata & Tyrrell P.C.
Nichols Christopher James
University of Medicine and Dentistry of New Jersey
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