Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Patent
1997-04-29
1999-06-01
Campell, Bruce R.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
435325, 4353201, 424 9321, 514 44, C07H 2104
Patent
active
059089237
ABSTRACT:
A method of using a transdominant negative integrase gene to make at least one cell resistant to a retroviral infection which includes retroviral infections resulting from HIV; a method for introducing a transdominant negative integrase gene into at least one mammalian cell to make said cell resistant to a retroviral infection as well as vectors, cells, and methods of constructing same useful in the aforementioned methods; a method of treating AIDS comprising administering to a patient an effective amount of a transdominant negative integrase gene alone or combined with agents useful for gene therapy inhibition of HIV, antiviral agents, or interleukin-2; and pharmaceutical delivery methods which include a transdominant negative integrase gene alone or combined with agents useful for gene therapy inhibition of HIV, antiviral agents, or interleukin-2.
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Holler Tod Paul
Meyer Annette
Nabel Gary Jan
Post Leonard
Campell Bruce R.
Nguyen Dave Trong
Tinney Francis J.
Warner-Lambert & Company
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