Multicellular living organisms and unmodified parts thereof and – Plant – seedling – plant seed – or plant part – per se – Higher plant – seedling – plant seed – or plant part
Patent
1998-07-28
2000-10-03
Smith, Lynette R. F.
Multicellular living organisms and unmodified parts thereof and
Plant, seedling, plant seed, or plant part, per se
Higher plant, seedling, plant seed, or plant part
800295, 800278, 536 241, 536 236, 536 237, 4353201, 435468, 435419, C12N 1500, C12N 1529, C12N 1582, A01H 500, A01H 400
Patent
active
061276065
ABSTRACT:
The invention discloses methods of controlling one or more genes in plants. The genes may be exogenous genes and produce a desired phenotypic trait in the plants produced. The genes are operatively linked to a heterologous upstream activating sequence (UAS) recognition site, which is activatable by a transactivating protein. The genes linked to the UAS sequence, and nucleic acid encoding for the transactivating protein may originally be in separate transgenic plants, one of which fertilizes the other to produce reproductive material, such as seed, which may be grown into plants expressing the desired phenotype. The desired phenotype may be herbicide resistance or the production of a polyhydroxyalkanoate, such as polyhydroxybutyrate.
REFERENCES:
patent: 5409823 (1995-04-01), Crossland et al.
patent: 5801027 (1998-09-01), Bennett et al.
Maas et al. Microbiol. Reviews. vol. 58(4), pp. 631-640, 1994.
University of Warwick, "Farmers could cultivate crops of plastic: New technique opens door to cheap cultivation of plastics in transgenic oilseed rape", Press Release, May 26, 1995.
Koning et al., "Arrest of embryo development in Brassica napus mediated by modified Pseudomonas aeruginosa exotoxin A", Plant Mol. Biol., vol. 18, pp. 247-258, (1992).
O'Kane et al., "Detection in situ of genomic regulatory elements in Drosophila", PNAS (USA), vol. 84, pp. 9123-9127, (1987).
Johnston, "A Model Fungal Gene Regulatory Mechanism: the GAL GEnes of Saccharomyces Cerevisiae", Microbiol. Rev., vol. 51 (4), pp. 458-476 (1987).
Ma et al., "Deletion Analysis of GAL4 Defines Two Transcriptional Activating Segments", Cell, vol. 48, pp. 847-853, (1987).
Brent et al., "A Eukaryotic Transcriptional Activator Bearing the DNA Specificity of a Prokaryotic Repressor", Cell, vol. 43, pp. 729-736, (1985).
West et al , "Saccharomyces cerecisiae GAL1-GAL10 Divergent Promoter Region: Location and Function of the Upstream Activating Sequence UAS.sub.G ", Mol. Cell. Biol., vol. 4 (11), pp. 2467-2478, (1984).
Giniger et al., "Specific DNA Binding of GAL4, A Positive Regulatory Protein of Yeast", Cell, vol. 40, pp. 767-774, (1985).
Lorch et al., "A Region Flanking the GAL7 Gene and a Binding Site for GAL4 Protein as Upstream Activating Sequences in Yeast", J. Mol. Biol., vol. 186, pp. 821-824, (1985).
Keegan et al., "Separation of DNA Binding from the Transcription-Activating Function of a Eukaryotic Regulatory Protein", Sci., vol. 231, pp. 699-704, (1986).
Johnston et al., "Genetic evidence that zinc is an essential co-factor in the DNA binding domain of GAL4 protein", Nature, vol. 328, pp. 353-355, (1987).
Marmorstein et al., "DNA recognition by GAL4: structure of a protein-DNA complex", Nature, vol. 356, pp. 408-414, (1992).
Carey et al., "An Amino-terminal Fragment of GAL4 Binds BNA as a Dimer", J. Mol. Biol. vol. 209, pp. 423-432, (1989).
Silver et al., "Amino terminus of the yeast GAL4 gene product is sufficient for nuclear localization", PNAS (USA), vol. 81, pp. 5951-5955, (1984).
Lin et al., GAL4 Derivatives Function Alone and Synergistically with Mammalian Activation in Vitro, Cell. vol. 54, pp. 659-664, (1988).
Kakidani et al., "GAL4 Activates Gene Expression in Mammalian Cells", Cell. vol. 52, pp. 161-167, (1988).
Webster et al., "The Yeast UAS.sub.G is a Transcriptional Enhancer in Human HeLa Cells in the Presence of the GAL4 Trans-Activator", Cell, vol. 52, pp. 169-178, (1988).
Ma et al., "Yeast activators stimulate plant gene expression", Nature, vol. 334, pp. 631-633, (1988).
Brand et al., "Targeted gene expression as a means of altering cell fates and generating dominate phenotypes", Development, vol. 118, pp. 401-415, (1993).
Greig et al., "Homeotic genes autonomously specify one aspect of pattern in the Drosophila mesoderm", Nature, vol. 362, pp. 630-632, (1993).
Yanisch-Perron et al., "Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mp18 an pUC19 vectors", Gene, vol. 33, pp. 103-119, (1985).
Jefferson et al., "GUS fusions: .beta.-glucuronidase as a sensitive and versatile gene fusion marker in higer plants", EMBO J., vol. 6 (13), pp. 3901-3907, (1987).
Odell et al, "Identification of DNA sequences required for activity of the cauliflower mosaic virus 35S promoter", Nature, vol. 313, pp. 810-812, (1985).
Vancanneyt et al., "Construction of an intron-containing marker gene: Splicing of the intron in transgenic plants and its use in monitoring early events in Agrobacterium-mediated plant transformation", Mol.Gen.Gent.,vol. 220,pp. 245-250, (1990).
Weinmann et al., "A chimeric transactivor allows tetracyline-responsive gene expression in whole plants", The Plant Journal, vol. 5(4), pp. 559-569 (1994).
Poirier et al., "Polyhydroxybutyrate, a Biodegradable Thermoplastic, Produced in Transgenic Plants", Science, vol. 256, pp. 520-523 (1992).
Mariani C. et al, "Induction of Male-Sterility in Plants By A Chimeric Ribonnuclease Gene", Nature, vol. 347, pp. 737-741 (1990).
Smith C. J. et al., "Antisense RNA Inhibition of Polygalacturonase Gene-Expression In Transgenic Tomatoes", Nature, vol. 334, pp. 724-726, (1988).
Hamilton A. J. et al., "Antisense Gene That Inhibits Synthesis of the Hormone Ethylene In Transgenic Plants", Nature, vol. 346, pp. 284-287., 1990, (1990).
Zambryski P. et al, "Ti Plasmid Vector for the Introduction of DNA into Plant Cells Without Alteration of Their Normal Regeneration Capacity", EMBO, vol. 2, No. 2, 2143-50, (1983).
Becker, et al., "New Plant Binary Vectors with Selectable Markers Located Proximal to The Left T-DNA Border", Plant Molecular Biology, vol. 20, No. 6, 1195-1197, (1992).
Meyer P. and Saedler H. Ann., "Homology-Dependent Gene Silencing in Plants", Annu. Rev. Plant Physiol. Plant Mol. Biol., vol. 47, pp. 23-48, (1996).
Baulcombe, D.C.; English, James J., Ectopic Pairing of Homologous DNA and Post-Transcriptional Gene Silencing in Transgenic Plants, Curr. Opin. Biotech., vol. 7, No. 2, pp. 173-180, (1996).
Bennett Malcolm
May Sean
Ramsay Nicola
Haas Thomas
Smith Lynette R. F.
University of Warwick
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