Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1992-06-17
1996-01-30
Draper, Garrette D.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
514 8, 514 21, 514886, 514 12, 424852, A61K 3816, C07K 14705
Patent
active
054880327
ABSTRACT:
Methods of using shulL-1Rs to suppress IL-1 mediated inflammation in a mammal.
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Bird et al., Identification of a comon class of high affinity receptors for both types of porcine IL-1 on connective tissue cells, Nature 324:263 (1986).
Kilian et al., Interleukin 1.alpha. and Interleukin 1.beta. Bind to the Same receptor on T Cells, J. Immunol. 136:4509, (1986).
Shirikawa et al., Expression of Interleukin 1 Receptors on Human Peripheral T Cells, J. Immunol. 138:4243 (1987).
Thieme et al., Recombinant Murine and Human IL-1.alpha. Bind to Human Endothelial Cells with an Equal Affinity . . . Lymphocytes, J. Immunol 139:1173 (1987).
Chin et al., Identification of a High-Affinity Receptor for Native Human Interleukin 1.beta. and Interleukin 1.alpha. on Normal Human Lung Fibroblasts, J. Exp. Med 165:70 (1987).
Bron et al., Identification of the plasma membrane receptor for interleukin -1 on mouse thymoma cells, FEBS 219:365 (1987).
Oppenheim et al., There is more than one interleukin 1, Immunol. Today 7:45 (1986).
Dower et al., The cell surface receptors for interleukin-1.alpha. and interleukin 1.beta. are identical, Nature 324:266 (1986).
Dower et al., The interleukin -1 receptor, Immunol. Today 8:46, (1987).
Dower Steven K.
March Carl J.
Sims John E.
Urdal David L.
Draper Garrette D.
Immunex Corporation
Malaska Stephen L.
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