Method of using silicon carbide for removal of adventitious...

Details Method of using silicon carbide for removal of adventitious... Method of using silicon carbide for removal of adventitious...

2006-12-13

2008-10-07

Barry, Chester T. (Department: 1797)

Liquid purification or separation

Processes

Chromatography

C210S660000, C210S679000, C210S690000

Reexamination Certificate

active

07431842

ABSTRACT:
A method of using silicon carbide for removing adventitious materials such as endotoxins, prions, viruses and bacteria from water, buffers, aqueous solutions or biological preparations of DNA or proteins, or any combination thereof. The present invention provides for a method of removing adventitious materials from a fluid by passing the fluid through a column or filter bed comprised of silicon carbide particles, or by passing the fluid through a silicon carbide slurry. The method reduces at least 90% of bacteria and endotoxins. It is an economical, reproducible and regenerable process for removing adventitious materials from various fluids.

REFERENCES:
patent: 5830360 (1998-11-01), Mozayeni
patent: 6565754 (2003-05-01), Codignola et al.
patent: 2004/0198845 (2004-10-01), Wang et al.
patent: 2006/0110308 (2006-05-01), Gupta et al.
patent: 2007/0037225 (2007-02-01), Metzger et al.
patent: 59059233 (1984-04-01), None

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