Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1990-02-23
1991-02-05
Springer, David B.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
A61K 3142
Patent
active
049905198
ABSTRACT:
This invention relates to novel quinolyloxazole-2-ones which are useful as protein kinase C inhibitors, effective in the treatment of hypertension and asthma. This invention also includes a novel procedure for producing an intermediate ketone compound involving the reaction of a bromo-quinoline compound with butyl lithium and further reacting the lithiated compound with N-methyl-N-methoxyalkanamide.
REFERENCES:
patent: 4670450 (1987-06-01), Schnettler et al.
patent: 4698353 (1987-10-01), schnettler et al.
patent: 4866085 (1989-09-01), Schnettler et al.
Cheng Hsien C.
Claxton George P.
Dage Richard C.
Jones Winton D.
Robinson Phillip J.
Merrell Dow Pharmaceuticals
Springer David B.
Stein William J.
LandOfFree
Method of using quinolyloxazole-2-ones as proteinkinase C inhibi does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method of using quinolyloxazole-2-ones as proteinkinase C inhibi, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of using quinolyloxazole-2-ones as proteinkinase C inhibi will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-10646