Method of using over the counter swab kit for self detection of

Details Method of using over the counter swab kit for self detection of Method of using over the counter swab kit for self detection of

1981-06-19

1982-07-20

Serwin, Ronald E.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving oxidoreductase

23230B, 422 61, 435 37, 435295, 435810, 435871, G01N 3350, C12K 100

Patent

active

043406700

ABSTRACT:
An over the counter swab kit for self detection of gonorrhea in the male using an ampul containing 1% N, N, N' N' tetramethyl-p- phenylenediamene or tetramethyl chromogen. The method of taking a sample is also shown in which the open end of a tube is filled with a plug in the form of fibrous material. After a sample is taken of exudate from a male, the 1% solution of tetramethyl chromogen reacts with Neisseria gonorrhea which may be present in the exudate to produce a color change. The plug, before the test, is in a dry condition, the plug is activated only by the tetramethyl chromogen which is placed below the plug in the tube and the ampul broken to release its contents. A sufficient amount of 1% tetramethyl chromogen is held within the frangible ampul to wet the plug and this amount is 1/2 the volume than is used in the saline ampul in my companion patent application entitled Over the Counter Swab Kit for Self Detection of Gonorrhea in the Male Using Saline Ampul. This volume is drawn by capillary action through the tip on which the sample of exudate was placed and before the ampul was broken. A purple color is created on the tip in 3 minutes at the site of the bacteria and is a positive test for gonorrhea. A key feature of the kit is the cover which protects the tip before use in self diagnosis is removed to take the specimen of exudate, and is replaced when the kit is inverted and the ampul broken to get the color change to purple in 3 minutes. If the deep purple color does not develop this is a negative test.

REFERENCES:
patent: 3446596 (1969-05-01), Salivar et al.
patent: 3954563 (1976-05-01), Mennen
patent: 3954564 (1976-05-01), Mennen
patent: 4272479 (1981-06-01), Huneke et al.
patent: 4300910 (1981-11-01), Pannwitz

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