Method of using (H+/K+) ATPase inhibitors as antiviral agents

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C514S307000, C514S322000

Reexamination Certificate

active

06906078

ABSTRACT:
A class of compounds which are (H+/K+)ATPase inhibitors can be used for the treatment of viral infections. Compounds of particular interest are defined by Formula III:wherein D is N or CH; wherein R7is one or more radicals selected from hydrido, alkoxy, amino, cyano, nitro, hydroxyl, alkyl, halo, haloalkyl, carboxyl, alkanoyl, nitro, amino, alkylamino, amide, alkylamide, alkoxycarbonyl, alkylthio, alkylsulfinyl and alkylsulfonyl; wherein R9is one or more radicals selected from hydrido, alkoxy, amino, alkyl, halo, cyano, nitro, hydroxyl, haloalkyl, carboxyl, alkanoyl, nitro, amine, alkylamine, dialkylamine, amide, alkylamide, alkoxycarbonyl, alkylthio, alkylsulfinyl and alkylsulfonyl; and wherein R10and R11are independently selected from hydrido and alkyl; or a pharmaceutically acceptable salt thereof.

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