Surgery: light – thermal – and electrical application – Light – thermal – and electrical application – Thermal applicators
Patent
1994-01-28
1995-09-05
Cohen, Lee S.
Surgery: light, thermal, and electrical application
Light, thermal, and electrical application
Thermal applicators
128739, 128642, 128695R, 128713, 607122, A61B 1739, A61N 105
Patent
active
054475295
ABSTRACT:
A method of locating infarcted myocardial tissue in a beating heart includes the step of inserting an impedance measuring tip of a catheter into the chamber of the beating heart, particularly the left or right ventricle, and measuring the impedance of the endocardium at various locations within the chamber of the beating heart. The values measured are compared to impedance values with a predetermined range of values to identify an infarcted area of myocardium and distinguish such area from normal myocardium. The measurements are also compared to a range of values for an infarction border zone. In accordance with the invention, the infarction border zone may be located. The infarction border zone is a significant source of arrhythmia, and particularly of ventricular tachycardia. Further, in accordance with the methods of the present invention, the risk of arrhythmia in a beating heart may be substantially reduced or eliminated by ablating endocardium within the infarction border zone utilizing the same catheter tip. Impedance measurements may also be utilized to assess the adequacy of the electrode-tissue contact, particularly in a fluid filled body organ or cavity. Further, the effectiveness of the ablation of the tissue may be determined by determining the degree of heating of the tissue by measuring the change in impedance in the area of ablation.
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Myocardial Electrical Impedance Mapping of Ischemic Sheep Hearts and Healing Aneurysms-Circulation, vol. 87, pp. 188-207 (1993).
Chang Isaac
Foster Kenneth R.
Gottleb Charles D.
Marchlinski Francis E.
Mirotznik Mark S.
Catholic University of America
Cohen Lee S.
Huang Stephen
Petock Michael F.
Philadelphia Heart Institute
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