Method of using cytokine receptors on microorganism

Details Method of using cytokine receptors on microorganism Method of using cytokine receptors on microorganism

1993-08-27

1994-12-20

Nucker, Christine M.

Drug, bio-affecting and body treating compositions

Lymphokine

4241931, 42419711, 4242341, 4242571, 4242581, 4242741, 4352521, 4352528, 435879, 435849, 435922, 4352554, A61K 3902, A61K 39112, A61K 39108, A61K 3900

Patent

active

053744233

ABSTRACT:
Cytokine receptors for tumor necrosis factor e which are found on microorganisms may, if bound with exogenous TNF.alpha., enhance the response of natural killer cells activated by the microorganisms, or increase TNF.alpha. production by peripheral blood lymphocytes treated with the microorganisms. Microorganisms with receptor-bound exogenous TNF.alpha. have enhanced cellular invasion ability which may change the immune response thereto. Clinical and pharmaceutical applications of these discoveries are provided.

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