Method of using an elicitor to increase production of metabolite

Details Method of using an elicitor to increase production of metabolite Method of using an elicitor to increase production of metabolite

1994-11-04

1996-09-03

Naff, David M.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Using fungi

435 41, 435170, 4352402, 4352404, 435244, 4352541, C12N 500, C12N 502

Patent

active

055523072

ABSTRACT:
A method for culturing fungal and plant cells in a culture medium containing an elicitor to increase production of a metabolite produced by the cells. For example, tobacco leaves produce the metabolite nicotine and the nicotine is produced in significantly greater amounts when the tobacco is cultured in a elicitor-containing medium. The elicitor is an oxidized Bovine Serum Albumin (BSA), or a glycosylated BSA, or an oxidized lysozyme, or glycosylated lysozyme or azetidine-2-carboxylic acid. Further, metabolite production is increased 1000% over the production of the metabolite when an elicitor is not added during the culturing method.

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