Method of using an antibody to the TN antigen for the inhibition

Details Method of using an antibody to the TN antigen for the inhibition Method of using an antibody to the TN antigen for the inhibition

1994-12-30

1999-03-02

Caputa, Anthony C.

Drug, bio-affecting and body treating compositions

Immunoglobulin, antiserum, antibody, or antibody fragment,...

Binds specifically-identified oligosaccharide structure

4241481, 4241531, 4241541, 4241551, 435 7021, 435329, 4353391, 4353431, 435343, 4353432, 435344, 435451, 435452, 53038835, 5303875, 5303887, 53038873, 53038875, 5303888, A61K 3942, C07K 1628, C07K 1630, C07K 1610

Patent

active

058767169

ABSTRACT:
A monoclonal or other antibody to the carbohydrate antigen Tn can be used to inhibit or slow the progression of AIDS or ARC. The antigen can be used in a vaccine, for immunisation.

REFERENCES:
Zolla-Pazner et al. J. Virol Mtds 17:45-53, 1987.
Fahey et al., Clin Exp. Immunol. 88:1-5 1992.
Hansen et al. J. Virology 64:2833-2840, 1990.
Hansen et al. J. Virology 65:6461-6467, 1991.
Harris et al. Tibtech 11:42-44, 1993.
Kjelcken et al. Cancer Res. 48:2214-2220 1988.
Aguila et al. Immunochemica vol. II (2) pp. 1-4, Jun. 1988.
Cooper, "The Tools of Biochemistry", John Wiley + Sons, 1977, pp. 378-385.

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