Method of using alpha-1 acid glycoprotein on T-cells as a marker

Details Method of using alpha-1 acid glycoprotein on T-cells as a marker Method of using alpha-1 acid glycoprotein on T-cells as a marker

1986-06-25

1989-01-31

Warden, Robert J.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

436501, 436504, 436518, 436536, 436538, 436542, 436547, 436815, 436811, G01N 3353

Patent

active

048015334

ABSTRACT:
Alzheimer's Disease (AD) sufferers may be diagnosed by examination of T-cells from their peripheral blood. AD is marked by increased appearance of alpha-1 acid glycoprotein (AGP) on the surface of such cells. Among AD subjects normal for AGP, a subpopoulation exists which show elevated AMLR response as compared to age-matched controls. These tests may be used to diagnose AD or to screen possible therapeutic agents.

REFERENCES:
patent: 4728605 (1988-03-01), Fudenberg et al.

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