Solid material comminution or disintegration – Processes – With application of fluid or lubricant material
Reexamination Certificate
2006-01-31
2006-01-31
Rosenbaum, Mark (Department: 3725)
Solid material comminution or disintegration
Processes
With application of fluid or lubricant material
C424S489000
Reexamination Certificate
active
06991191
ABSTRACT:
A small-scale or micro media-mill and a method of milling materials or products, especially pharmaceutical products, use a dispersion containing attrition milling media and the product to be milled. The milling media can be polymeric, formed of polystyrene or cross-linked polystyrene, having a nominal diameter of no greater than 500 microns. Other sizes include 200 microns and 50 microns and a mixture of these sizes. The mill has a relatively small vessel having an opening, an agitator, a coupling and a motor. The agitator can have a rotor and a shaft extending therefrom. The rotor can be cylindrical or have other configurations, and can have tapered end surfaces. The coupling can close the vessel opening, or attaching the coupling to the motor can close the opening. The coupling has an opening through which the rotor shaft extends into the motor. A sealing mechanism, such as a mechanical or lip seals the shaft while permitting the rotor shaft to rotate. The vessel can contain one or more ports for circulating the dispersion, where milling can be made in batches or recirculated through the milling chamber. The media can be retained in the vessel or recirculated along with the process fluid. The rotor is dimensioned so that its outer periphery is spaced with a small gap from an inner surface of the vessel. The vessel also can have a way of cooling the dispersion.
REFERENCES:
patent: 4848676 (1989-07-01), Stehr
patent: 5133506 (1992-07-01), Bogen
patent: 5145684 (1992-09-01), Liversidge et al.
patent: 5183215 (1993-02-01), Getzmann
patent: 5464163 (1995-11-01), Zoz
patent: 5518187 (1996-05-01), Bruno et al.
patent: 5593097 (1997-01-01), Corbin
patent: 5718388 (1998-02-01), Czekai et al.
patent: 5797550 (1998-08-01), Woodall et al.
patent: 5862999 (1999-01-01), Czekai et al.
patent: 0483808 (1992-05-01), None
patent: 0686428 (1995-12-01), None
PCT International Search Report based on Appl. No. PCT/US00/014705.
Reinsch et al., “Energy Consumption for Wet Grinding in Stirred Mills,”Aufbereitungs-Technik, 38(1997) 3, pp. 152-160.
The et al., “Autogenous Grinding of SIC in Stirred Mills with- out and with Grinding Aids, Part 1,”Aufbereitungs-Technik, 33(1992) 10, pp. 541-549.
Joost et al., “Feinstzerkleinerung in Rührwerkmühien,”Das Jehrbuch der Keramik, Reh, H., Bauverlag, Walluf, 1995, pp. 23-38.
Stadler et al., “Nassmahlung in Rührwerksmühien,”Chem.-ing.-Tech., 82(1990) 11, pp. 907-915.
Kwade et al., “Motion and Stress intensity of grinding beads in a stirred media mill. Part 2: Stress intensity and its effect on comminution,”Powder Technology, 86(1996), pp. 69-76.
Bosch Henry William
Czekai David A.
Reed Robert Gary
Ryde Niels-Peter Moesgaard
Elan Pharma International Limited
Foley & Lardner LLP
Rosenbaum Mark
LandOfFree
Method of using a small scale mill does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method of using a small scale mill, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of using a small scale mill will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3581953