Method of using a matrix metalloproteinase inhibitor and one...

Details Method of using a matrix metalloproteinase inhibitor and one... Method of using a matrix metalloproteinase inhibitor and one...

2005-02-22

2005-02-22

Raymond, Richard L. (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C514S227500, C514S227800, C514S283000, C514S318000, C514S319000, C514S321000, C514S330000, C544S059000, C544S060000, C546S048000, C546S238000, C546S263000

Reexamination Certificate

active

06858598

ABSTRACT:
A method of using an MMP inhibitor and optionally radiation therapy, and one or more antineoplastic agents of the topoisomerase class selected from the group consisting of irinotecan and topotecan, as a combination therapy for the treatment of neoplasia is disclosed.

REFERENCES:
patent: 4100274 (1978-07-01), Dutta et al.
patent: 4105681 (1978-08-01), Bollag et al.
patent: 4140707 (1979-02-01), Cleare et al.
patent: 4215215 (1980-07-01), Bollag et al.
patent: 4310666 (1982-01-01), Zee-Cheng et al.
patent: 4472382 (1984-09-01), Labrie et al.
patent: 4596797 (1986-06-01), Schweikert et al.
patent: 5250683 (1993-10-01), Holton et al.
patent: 5254703 (1993-10-01), Holton
patent: 5272171 (1993-12-01), Ueda et al.
patent: 5319112 (1994-06-01), Kingston et al.
patent: 5344991 (1994-09-01), Reitz et al.
patent: 5455270 (1995-10-01), Kaplan et al.
patent: 5629343 (1997-05-01), Hagmann et al.
patent: 5633016 (1997-05-01), Johnson
patent: 5672583 (1997-09-01), Chapman et al.
patent: 5686419 (1997-11-01), Powers et al.
patent: 5696131 (1997-12-01), Baguley et al.
patent: 5733909 (1998-03-01), Black et al.
patent: 5767142 (1998-06-01), LaVoie et al.
patent: 5824699 (1998-10-01), Kreft et al.
patent: 5837696 (1998-11-01), Golub et al.
patent: 5869524 (1999-02-01), Failli
patent: 5952381 (1999-09-01), Chen et al.
patent: 6087392 (2000-07-01), Reiter
patent: 6110964 (2000-08-01), Robinson
patent: 6114361 (2000-09-01), Robinson et al.
patent: 6156798 (2000-12-01), Reiter
patent: 6214870 (2001-04-01), McClure et al.
patent: 195 48 798 (1997-07-01), None
patent: 196 13 933 (1997-10-01), None
patent: 196 26 701 (1998-01-01), None
patent: 0 010 458 (1980-04-01), None
patent: 0 054 168 (1982-06-01), None
patent: 0 095 875 (1983-12-01), None
patent: 0 165 904 (1985-12-01), None
patent: 0 199 636 (1986-10-01), None
patent: 0 236 940 (1987-09-01), None
patent: 0 260 744 (1988-03-01), None
patent: 0 299 402 (1989-01-01), None
patent: 0 331 983 (1989-09-01), None
patent: 0 402 232 (1990-12-01), None
patent: 0 532 156 (1993-03-01), None
patent: 0 579 915 (1994-01-01), None
patent: 0 640 594 (1995-03-01), None
patent: 0 702 962 (1996-03-01), None
patent: 0 703 239 (1996-03-01), None
patent: 0 716 086 (1996-06-01), None
patent: 0 743 070 (1996-11-01), None
patent: 0 758 649 (1997-02-01), None
patent: 0 818 443 (1998-01-01), None
patent: 0 882 734 (1998-12-01), None
patent: 0 921 119 (1999-06-01), None
patent: 1 081 137 (2001-03-01), None
patent: 1 088 550 (2001-04-01), None
patent: 1 134 215 (2001-09-01), None
patent: 1 138 680 (2001-10-01), None
patent: 2 282 598 (1995-04-01), None
patent: WO 8707609 (1987-12-01), None
patent: WO 9300427 (1993-01-01), None
patent: WO 9311145 (1993-06-01), None
patent: WO 9318652 (1993-09-01), None
patent: WO 9402466 (1994-02-01), None
patent: WO 9412169 (1994-06-01), None
patent: WO 9413635 (1994-06-01), None
patent: WO 9420480 (1994-09-01), None
patent: WO 9421612 (1994-09-01), None
patent: WO 9425431 (1994-11-01), None
patent: WO 9425466 (1994-11-01), None
patent: WO 9426731 (1994-11-01), None
patent: WO 9427980 (1994-12-01), None
patent: WO 9502603 (1995-01-01), None
patent: WO 9508327 (1995-03-01), None
patent: WO 9511883 (1995-05-01), None
patent: WO 9512606 (1995-05-01), None
patent: WO 9513289 (1995-05-01), None
patent: WO 9515316 (1995-06-01), None
patent: WO 9524199 (1995-09-01), None
patent: WO 9529892 (1995-11-01), None
patent: WO 9530652 (1995-11-01), None
patent: WO 9530656 (1995-11-01), None
patent: WO 9600214 (1996-01-01), None
patent: WO 9600574 (1996-01-01), None
patent: WO 9601653 (1996-01-01), None
patent: WO 9603387 (1996-02-01), None
patent: WO 9603392 (1996-02-01), None
patent: WO 9606840 (1996-03-01), None
patent: WO 9614745 (1996-05-01), None
patent: WO 9615096 (1996-05-01), None
patent: WO 9621667 (1996-07-01), None
patent: WO 9623791 (1996-08-01), None
patent: WO 9627583 (1996-09-01), None
patent: WO 9633988 (1996-10-01), None
patent: WO 9635774 (1996-11-01), None
patent: WO 9636335 (1996-11-01), None
patent: WO 9636612 (1996-11-01), None
patent: WO 9636622 (1996-11-01), None
patent: WO 9636623 (1996-11-01), None
patent: WO 9637469 (1996-11-01), None
patent: WO 9711693 (1997-04-01), None
patent: WO 9715666 (1997-05-01), None
patent: WO 9715676 (1997-05-01), None
patent: WO 9719068 (1997-05-01), None
patent: WO 9719954 (1997-06-01), None
patent: 9720824 (1997-06-01), None
patent: WO 9720835 (1997-06-01), None
patent: 9720824 (1997-07-01), None
patent: WO 9723459 (1997-07-01), None
patent: WO 9724116 (1997-07-01), None
patent: WO 9729106 (1997-08-01), None
patent: WO 9731936 (1997-09-01), None
patent: WO 9734608 (1997-09-01), None
patent: WO 9736497 (1997-10-01), None
patent: WO 9736863 (1997-10-01), None
patent: WO 9737658 (1997-10-01), None
patent: WO 9741844 (1997-11-01), None
patent: WO 9744315 (1997-11-01), None
patent: WO9720824 (1997-12-01), None
patent: WO 9747296 (1997-12-01), None
patent: WO 9747599 (1997-12-01), None
patent: WO9748685 (1997-12-01), None
patent: WO 9748685 (1997-12-01), None
patent: 9748685 (1997-12-01), None
patent: WO 9749704 (1997-12-01), None
patent: WO 9803166 (1998-01-01), None
patent: WO 9803484 (1998-01-01), None
patent: WO 9803516 (1998-01-01), None
patent: WO 9805635 (1998-02-01), None
patent: WO 9807433 (1998-02-01), None
patent: WO 9808814 (1998-03-01), None
patent: WO 9808850 (1998-03-01), None
patent: WO 9812181 (1998-03-01), None
patent: WO 9813350 (1998-04-01), None
patent: WO 9814188 (1998-04-01), None
patent: WO 9815525 (1998-04-01), None
patent: WO 9816227 (1998-04-01), None
patent: WO 9822101 (1998-05-01), None
patent: WO 9822101 (1998-05-01), None
patent: WO 9825603 (1998-06-01), None
patent: WO 9825896 (1998-06-01), None
patent: WO 9827069 (1998-06-01), None
patent: WO 9830566 (1998-07-01), None
patent: WO 9833768 (1998-08-01), None
patent: WO 9833788 (1998-08-01), None
patent: WO 9840104 (1998-09-01), None
patent: WO 9845294 (1998-10-01), None
patent: WO 9847890 (1998-10-01), None
patent: WO 9901131 (1999-01-01), None
patent: WO 9905104 (1999-02-01), None
patent: WO 9910331 (1999-03-01), None
patent: WO 9912930 (1999-03-01), None
patent: WO 9914194 (1999-03-01), None
patent: WO 9914205 (1999-03-01), None
patent: WO 9921583 (1999-05-01), None
patent: WO 9923087 (1999-05-01), None
patent: WO9921583 (1999-06-01), None
patent: WO 9931067 (1999-06-01), None
patent: WO 9941241 (1999-08-01), None
patent: WO 0009485 (2000-02-01), None
patent: WO 0009492 (2000-02-01), None
patent: WO 0073294 (2000-12-01), None
patent: WO 0112611 (2001-02-01), None
patent: WO 0140216 (2001-06-01), None
Carter et al., Chemotherapy of Cancer, Second Edition, John Wiley & Sons, N.Y.,N.Y., 362-365(1981).*
M.D.Anderson et al, Seminars in Oncology, 23/5, Suppli. 11,46-58(1996) also cited as Chemical Abstract DN125:316004.*
Relias et al, J. Oncology Pharmacy Practice, 3/4. 173-185(1997).,also cited as Chemical Abstract DN 128:212465.*
Zook et al, Chemical Abstract DN 127:108945 also cited as WO 9720824.*
Webster's DictionaryISBN: 0-395-33957-X p. 933.*
Novotny et al(PubMed12745645, also cited as Hematology, 8/3, 129-37(2003).*
Barni Sandro et al;Biological Abstracts prev 199800349798 XP002133936 & Tumori,vol. 84 No. 1, Feb. 1998-02, pp. 45-47.*
Muller-Bohn T, Deutsche Apotheker Zeitung, 137/41, 54-55(1997).*
Heath et al;“Clinical potential of MMPI in cancer ther.”;PubMed Abst.:10852638, also Drugs May 2000; 59/5, 1043-55.*
Belotti et al;“MMPI:experimental and clinical studies”;PubMed Abst.:10669951, also Int J. Biol Markers Oct.-Dec.; 14/4,232-8.*
Liekens et al;“Angigenesis:regulators and clinical appli.”;PubMed Abst. 11172729, also Biochm. Pharmacol Feb. 1, 2001; 61/3,253-70.*
Hidalgo et al;“Dev. of MMPI in cancer therapy”;PubMed Abst. 11158186, also J. Natl Cancer Inst. Feb. 7, 2001; 93/3, 178-93.*
Biological Abstracts, vol. 00, Philadelphia, PA, USA Barni, Sandro et al: “Clinical efficacy of the aromatase inhibitor anastrozole in relation to prolactin secretion in heavily pretreated metastatic breast cancer”.
Comis R.L. et al: “Small-cell lung

Affiliated with

Also associated with

Rating

Method of using a matrix metalloproteinase inhibitor and one... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method of using a matrix metalloproteinase inhibitor and one..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of using a matrix metalloproteinase inhibitor and one... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3472805