Chemistry: analytical and immunological testing – Cancer
Patent
1990-06-15
1992-11-10
Lacey, David L.
Chemistry: analytical and immunological testing
Cancer
435119, 435968, 514410, 514185, 436800, 436805, 436519, G01N 3348
Patent
active
051622319
ABSTRACT:
Method using tetra-aryl porphyrins for and, in particular, 5,10,15,20-tetrakis(4-carboxyphenyl)porphine as a fluorescent tracer for cancers of the lung, and as a radiotracer therefor as a complex with .sup.67 Cu. The latter complex also provides a source of beta radiation for selective destruction of lung malignancies as well as gamma radiation useful for image analysis of the situs thereof by single photon emission computed tomography, as an example, both in vivo. Copper-64 may be substituted for the .sup.67 Cu if only radiotracer characteristics are of interest. This lighter isotope of copper is a positron emitter, and positron emission tomography techniques cna be used to locate the malignant tissue mass.
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Cole Dean A.
Ellinwood L. Edward
Klein M. Gerard
Moody, III David C.
Daley Thomas E.
Lacey David L.
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