Method of using 1H-pyrimido-4,5-c -1,2-diazepines as antibacteri

Details Method of using 1H-pyrimido-4,5-c -1,2-diazepines as antibacteri Method of using 1H-pyrimido-4,5-c -1,2-diazepines as antibacteri

1979-09-17

1982-02-16

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

2602433, 544256, 544262, 544279, 544320, 544321, 544325, A61K 31505, C07D48704

Patent

active

043159320

ABSTRACT:
Compounds of the general formula (I) ##STR1## wherein R.sup.1 and R.sup.2 are selected from a lower alkyl group, a phenyl group (optionally substituted by one or more hydroxy or lower alkoxy groups), a pyridyl group or a group --CO.sub.2 R where R is a lower alkyl group, (provided that when R.sup.1 is a group --CO.sub.2 R, R.sup.2 is a lower alkyl group) are disclosed.
The compounds of formula (I) are useful as intermediates to compounds of other ring systems which are of pharmacological interest.
Certain of the compounds of formula (I) are also useful as antimicrobial agents.

REFERENCES:
patent: 3947442 (1976-03-01), Beckwith
Airano, "Chemical Abstracts", vol. 52, 1958, col. 3838e.
"Chemical Abstracts", vol. 84, 1976, col. 59531m.

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