Method of treatment using mouthwashes containing steroids and an

Details Method of treatment using mouthwashes containing steroids and an Method of treatment using mouthwashes containing steroids and an

1993-01-15

1994-05-10

Cintins, Marianne M.

Drug, bio-affecting and body treating compositions

Dentifrices

514171, A61K 728, A01N 4500

Patent

active

053105451

ABSTRACT:
Compositions used to treat inflammatory diseases of the mouth contain anti-inflammatory steroids in combination with antifungal drugs in an aqueous medium as a mouthwash. Swishing for three to five minutes, then expectorating the mouthwashes results in maintenance of contact of the active agents with the oral cavity surfaces for a longer time than would application of gels containing those agents. The mode of application is simple and is not repugnant to the patient as is the application of creams, gels, or ointments.

REFERENCES:
United States Pharmacopeia, 1980, p. 563.
Rothwell et al., Special Care in Dentistry, Palliation of Radiation-related Mucositis, Jan.-Feb. 1990, pp. 21-25.
Merck Index, entries 213, 1202, 2361, 2362, 2412, 6658, 6692, 9511; 1989.
Goodman et al., The Pharmacological Basis of Therapeutics, MacMillan, 1975, p. 1491.

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