Drug – bio-affecting and body treating compositions – Enzyme or coenzyme containing – Hydrolases
Reexamination Certificate
2011-08-16
2011-08-16
Ariani, Kade (Department: 1651)
Drug, bio-affecting and body treating compositions
Enzyme or coenzyme containing
Hydrolases
C435S225000
Reexamination Certificate
active
07998476
ABSTRACT:
A method for treating various diseases, conditions and injuries with a protease preparation derived fromAspergillus orzyzeand made using potato dextrin as the carbohydrate source is described. The method comprises orally administering theAspergillus oryzaeprotease preparation on an empty stomach and in an amount greater than about 2,000,000 HUT per day. Additionally, a method for treating various diseases, conditions and injuries with a protease derived fromAspergillus oryzaemade using potato dextrin as the carbohydrate source along with a nutritional supplement of vitamins and minerals is also described. The method comprises orally administering theAspergillus oryzaeprotease preparation on an empty stomach in an amount of greater than 2,000,000 HUT per day and administering the dietary supplement of vitamins and minerals orally with food.
REFERENCES:
patent: 3905869 (1975-09-01), Hidaka et al.
patent: 3932618 (1976-01-01), Fujii et al.
patent: 3940478 (1976-02-01), Kurtz
patent: 4844897 (1989-07-01), Maeda et al.
patent: 5500359 (1996-03-01), Boyer et al.
patent: 5560910 (1996-10-01), Crandall
patent: 5560914 (1996-10-01), Ghoneum et al.
patent: 5562900 (1996-10-01), Boyer et al.
patent: 5662902 (1997-09-01), Boyer et al.
patent: 5662903 (1997-09-01), Boyer et al.
patent: 6361800 (2002-03-01), Cooper et al.
patent: 6413512 (2002-07-01), Houston et al.
patent: 6953588 (2005-10-01), Cooper et al.
patent: 7067124 (2006-06-01), Davidson et al.
patent: 2003/0095961 (2003-05-01), Houston et al.
patent: 2004/0057944 (2004-03-01), Galle et al.
patent: 2004/0191237 (2004-09-01), Davidson et al.
patent: 2005/0214383 (2005-09-01), Bubnis et al.
patent: 2005/0244510 (2005-11-01), Smith
patent: 2006/0216361 (2006-09-01), Edwards et al.
patent: 1 293 227 (1972-10-01), None
patent: 1 390 542 (1975-04-01), None
patent: WO 94/25580 (1994-11-01), None
patent: WO 95/08998 (1995-06-01), None
patent: WO 02/060474 (2002-08-01), None
Sarzi-Puttini et al. , Seminars in Arthritis and Rheumatism, 2005, vol. 35 (Suppl), p. 1-10.
Protease A-DS, Enzyme Material Safety Data Sheet , AMANO Enzyme Inc., Issue date Jan. 3, 2003.
Wierik et al., International Journal of Pharmaceutics, 1996, vol. 134, p. 27-36.
“Digestive Disorders,” as presented by LifeExtension <www.lef.org> updated Jun. 5, 2003, accessed on Jul. 9, 2008.
“Dr. Gonzalez, Individualized Nutritional Protocols,” as presented by Dr.Gonzalez.com <www.dr-gonzalez.com> accessed Jul. 15, 2008.
“Enzymes Derived fromAspergillus oryzae,” as presented by IPCS Inchem <www.inchem.org> accessed Jul. 11, 2008.
“Enzymes in use for dietary purposes in the U.S. prior to Oct. 1994,” as presented by the Enzyme Technical Association <www.enzymetechnicalassoc.org> last revised Jan. 1999, accessed Jul. 11, 2008.
“Enzymes to Improve Immune system Health-Protease and Cancer” as presented by HealthyNewAge <www.healthynewage.com> accessed Jul. 15, 2008.
“Expert Interview: Antiangiogenesis for Colorectal Cancer—an Evolving Therapeutic Strategy: An Expert Interview With Dr. Herbert Hurwitz,” as presented byMedscape Medical News<www.medscape.com> released Jun. 21, 2006, accessed Jul. 9, 2008.
“Holistic Health Information—Enzymes, Herbs and Prostate Cancer,” as presented by HealthyNewAge <www.healthynewage.com> accessed Jul. 15, 2008.
“N.D.M., Nutrition, L.L.C.,” <www.ndmnutrition.com> accessed Jul. 15, 2008.
“Nutritional Therapeutics Division of Standard Biologics, Inc.™,” <nutritionaltherapeutics.com> accessed Jul. 15, 2008.
“Protease,” as presented by Greenwood Health Systems <www.greenwoodhealth.net> accessed Jul. 10, 2006.
“The Healing Power of Proteolytic Enzymes,” Dr. Murray, Natural Living, as presented by DoctorMurray.com <www.doctormurray.com> accessed Jul. 15, 2008.
“The Science of ProZime-440™,” as presented by ProVision Naturals™ <www.provisionnaturals.com> accessed Jul. 11, 2008.
Ackerson, A., et al., “Nutritional Support of Osteoporosis,” as presented by HealingYou <www.healingyou.org> accessed Jul. 11, 2008.
Amano Enzyme product List Copyright © 2007.
Andersen, G.D., “Proteolytic Enzymes—Part III,”Dynamic Chiropractic 9, as presented by Chiroweb <www.chiroweb.com> accessed Jul. 11, 2008.
Aprahamian, M., et al., “Efficiency of pantothenic acid on wound healing: effect of an increase of iron and copper content of the tissues,”Eur. Surg. Res. 15:61, Abstract No. 96, Karger (1983).
Banford, J.C., et al., “Serum copper and erythrocyte superoxide dismutase in rheumatoid arthritis,”Ann. Rheum. Dis. 41:458-462, BMJ Publishing Group (1982).
Barclay, L., “Older Adults May Need B12 Dose More Than 200 times the RDA to Normalize Mild Vitamin Deficiency,” as presented byMedscape Medical News<www.medscape.com> released May 27, 2005, accessed Jul. 14, 2008.
Barton-Wright, E.C and Elliot, W.A., “The Pantothenic Acid Metabolism of Rheumatoid Arthritis,,”Lancet 2:862-863, Lancet Publishing Group (1963).
Berdanier, C.D., “Integration of the Functional Aspects of Vitamins and Minerals,” inAdvanced Nutrition Micronutrients, Unit 2, CRC Press LLC, Boca Raton, Florida, pp. 9-20 (1998).
Berger, B., et al., “Useful hydrolytic enzymes: Proteases, lipases and nitrilases,”Pure&Appl. Chem. 64:1085-1088, International Union of Pure and Applied Chemistry (1992).
Bergkvist, R., “The Proteolytic Enzymes ofAspergillus oryzae, II: Properties of the Proteolytic Enzymes,”Acta. Chem. Scand. 17:1541-1551, Munksgaard International Publishers (1963).
Biesebeke, R., et al., “Branching mutants ofAspergillus oryzaewith improved amylase and protease production on solid substrates,”Appl. Microbiol. Biotechnol. 69:44-50, Springer Verlag (Nov. 2005).
Bitomsky, M., “Digestive Enzymes: the Missing Link,”LE Magazine, Life Extension Foundation (1999).
Black Hills Health Products, Inc. information on enzyme supplements as presented by NDMnutrition <www.ndmnutrition.com> accessed Jul. 2, 2006.
Brouillette, K.M., ed., “Chapter 13: The Musculoskeletal System,” inAthletic Training and Sports Medicine, American Academy of Orthopaedic Surgeons, Park Ridge, IL, pp. 192-202 (1991).
Combs, G.F., “Chapter 6: Vitamin D,” inThe Vitamins: Fundamental Aspects in Nutrition and Health, Academic Press, San Diego, CA, pp. 151-178 (1992).
Crewther, W.G. and Lennox, F.G., “Enzymes ofAspergillus oryzae. IV. Fractionation and Preparation of Crystals Rich in Protease,”Aust. J. Sci. Res. 6:429-446, Commonwealth Scientific and Industrial Research Organization (1953).
Crewther, W.G. and Lennox, F.G., “Preparation of Crystals Containing Protease fromAspergillus oryzae,” Nature 165:680, Nature Publishing Group (1950).
Diffang, C. and Saldeen, T., “Effect of Brinase (Protease I fromAspergillus oryzae) on the Elimination of Fibrin from the Lungs and Pulmonary Damage in Rats with Induced Intravascular Coagulation and Inhibited Fibrinolysis,”Thromb. Res. 9:611-622, Pergamon Press (1976).
Doi, Y., et al., “Substrate Specificities of Deuterolysin fromAspergillus oryzaeand Electron Paramagnetic Resonance Measurement of Cobalt-substituted Deuterolysin,”Biosci. Biotechnol. Biochem. 67:264-270, Japan Society for Bioscience, Biotechnology, and Agrochemistry (2003).
Donoho, C.R., and Rylandee, C.R., “Proteolytic Enzymes in Athletic Injuries a Double-Blind Study of a New Anti-Inflammatory Agent,”Del. Med. J. 34:168-170, Medical Society of Delaware (1962).
Dryburgh, D.R., “Vitamin C and Chiropractic,”J. Manip. Physiol. Ther. 8:95-103, National University of Health Sciences (1985).
Dunham, J., “Chapter 1: Metaboli
Ariani Kade
Nevrivy Patent Law Group P.L.L.C.
Standard Biologics, Inc.
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