Method of treatment using a therapeutic combination of .alpha. i

Drug – bio-affecting and body treating compositions – Lymphokine – Interferon

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

424 857, 514 18, A61K 3821

Patent

active

058304550

ABSTRACT:
The present invention relates to a therapeutic combination therapy involving the use of human interferon. The therapy involves the treatment of conditions susceptible to treatment with human interferon, with a combination of a human interferon and a free radical scavenger or precursor or inducer.

REFERENCES:
patent: 4100150 (1978-07-01), Cartwright
patent: 4762705 (1988-08-01), Rubin
patent: 4927762 (1990-05-01), Darfler
patent: 4985241 (1991-01-01), Zimmerman et al.
patent: 5080906 (1992-01-01), Carenzi et al.
patent: 5248697 (1993-09-01), Wilmore
Bisceglie et al., N. Eng. J. Med., vol. 321 (22), pp. 1506-1510, 1989.
Van der Nuy, Pharm. Weekbl., vol. 121(29), pp. 646-649, 1986.
Jose Vina et al., Br. J. Nutr., vol. 62(3), pp. 683-691, 1989.
Wells, Prog. Clin. Biol. Res., vol. 135, pp. 367-371, 1983.
Bridgeman et al., Thorax, vol. 46(1), pp. 39-42, 1991.
Beloqui, O et al., J. Interferon Res., vol. 13, pp. 279-282, 1993.
Ahezzi et al., Cancer Res., vol. 45, pp. 3444-3447, 1985.
Ahezzi et al., J. Interferon Res., vol 6, pp. 251-256, 1986.
Schor, "Mechanisms of Synergistic Toxicity of the Radioprotective Agent, WR2721, And 6-Hydroxydopamine", Biochemical Pharmacology 37(9):1751-1762 (1988).
Tabachnik et al, "Studies on the Reduction of Sputum Viscosity in Cystic Fibrosis Using an Orally Absorbed Protected Thiol", The Journal of Pharmacology and Experimental Therapeutics 214(2) 246-249 (1980).
Shirota et al, "Failure of glutathione and cystein prodrugs to block the chlorpropamide-induced inhibition of aldehyde dehydrogenase in vivo", Biochemical Pharmacology 43(4):916-918 (1992).
Porta et al, "L-2-Oxothiazolidine-4-Carboxylic Acid, a Cysteine Prodrug: Pharmacokinetics and Effects on Thiols in Plasma and Lymphocytes in Human", The Journal of Pharmacology and Experimental Therapeutics 257(1):331-334 (1991).
Hazelton et al, "Effects of Cysteine Pro-Drugs on Acetaminophen-Induced Hepatotoxicity", The Journal of Pharmacology and Experimental Therapeutics 237(1):341-349 (1986).
Trepo et al, "Treatment of chronic hepatitis C", Therapy in Liver Diseases, pp. 253-258 (1992), eds J. Rodes/V. Arroyo, Ediciones Doyma SA.
Roederer M. et al., Aids Research and Human Retroviruses, vol. 8 No. 2 (1992) pp. 209-217.
Kitamura Y. et al., The Journal of Pharmacology and Experimental Therapeutics, vol. 25-No. 2 (1988) pp. 667-671.
Roberts J.C. et al., J. Med. Chem., vol. 30 (1987) pp. 1891-1896.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Method of treatment using a therapeutic combination of .alpha. i does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method of treatment using a therapeutic combination of .alpha. i, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of treatment using a therapeutic combination of .alpha. i will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-686636

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.