Drug – bio-affecting and body treating compositions – Lymphokine – Interleukin
Reexamination Certificate
2007-10-09
2007-10-09
Nickol, Gary B. (Department: 1647)
Drug, bio-affecting and body treating compositions
Lymphokine
Interleukin
C425S085000, C514S012200
Reexamination Certificate
active
10679201
ABSTRACT:
The present invention relates to the use of a cytokine-1, preferably from the IL-1 family more preferably IL-1F7b, or an isoform, mutein, fused protein, functional derivative or fragment thereof, capable of binding to IL-18BP or a mutein, fused protein, functional derivative or fragment thereof and capable of inhibiting a receptor of a cytokine-2, cytokine-2 being a member of the IL-1 family, preferably IL-18, in the manufacture of a medicament for the treatment or prevention of a disease which is caused or aggravated by inducing said receptor of cytokine-2.
REFERENCES:
patent: 5194596 (1993-03-01), Tischer et al.
patent: 5350836 (1994-09-01), Kopchick et al.
patent: 5945310 (1999-08-01), Young et al.
patent: 6342371 (2002-01-01), McDonnell et al.
patent: WO99/37772 (1999-07-01), None
patent: WO 01/40247 (2001-06-01), None
patent: WO 0140247 (2001-06-01), None
Vukicevic et al., 1996, PNAS USA 93:9021-9026.
Massague, 1987, Cell 49:437-8.
Pilbeam et al., 1993, Bone 14:717-720.
Skolnick et al., 2000, Trends in Biotech. 18:34-39.
Bork, 2000, Genome Research 10:398-400.
Doerks et al., 1998, Trends in Genetics 14:248-250.
Smith et al., 1997, Nature Biotechnology 15:1222-1223.
Brenner, 1999, Trends in Genetics 15:132-133.
Bork et al., 1996, Trends in Genetics 12:425-427.
Bowie et al, 1990, Science 247:1306-1310.
Wells, 1990, Biochemistry 29:8509-8517.
Thomson et al., Eds. The Cytokine Handbook, vol. 2, Fourth Edition, Academic Press, San Diego, CA. 2003, pp. 653-656, 740-741.
Arthritis Foundation, Disease Center, Feb. 7, 2007.
Pan et al., Cytokine Jan. 7, 2001 13(1):1-7).
Kumar et al., Cytokine Apr. 21, 2002 18(2):61-71.
NCBI accession No. AF200496, accessed May 9, 2006.
Benjamin et al., 1998, Development 125:1591-1598.
English translation of Kashiwamura, S. et al.; Nippon Rinsho; 56(7): 1798-1806 (1998).
Azam, T. et al.; The Journal of Immunology; 171:6574-6580 (2003).
Barton, J.L. et al.; Eur. J. Immunol.; 30:3299-3308 (2000).
Born, T.L. et al.; The Journal of Biological Chemistry; 273(45):29445-29450 (1998).
Busfield, S.J. et al.; Genomics; 66:213-216 (2000).
Corbaz, A. et al.; The Journal of Immunology; 168:3608-3616 (2002).
Debets, R. et al.; The Journal of Immunology; 167:1440-1446 (2001).
Dinarello, C.A.; Eur. Cytokine Netw.; 11:483-486 (2000).
Dinarello, C.A.; Blood, 87(6):2095-2147 (1996).
Gracie, J.A. et al.; J. Clin. Invest.; 104:1393-1401 (1999).
Kim, S.H. et al.; The Journal of Immunology; 166:148-154 (2001).
Kim, S.H. et al.; PNAS; 97(3):1190-1195 (2000).
Kumar, S. et al.; The Journal of Biological Chemistry; 275(14):10308-10314 (2000).
Kumar, S. et al.; Cytokine; 18(2):61-71 (2002).
Lin, H. et al.; The Journal of Biological Chemistry; 276(23):20597-20602 (2001).
Mallat, Z. et al.; Cir. Res.; 91:441-448 (2002).
Monteleone, G. et al.; The Journal of Immunology; 163:143-147 (1999).
Mulero, J.J. et al.; Biochemical and Biophysical Research Communications; 263:702-706 (1999).
Nakanishi, K. et al.; Annu. Rev. Immunol.; 19:423-474 (2001).
Novick, D. et al.; Immunity; 10:127-136 (1999).
Novick, D. et al., Cytokine, 14:334-342 (2001).
Ohta, Y. et al.; Arch. Derm. Res.; 293(7):334-42 (2001).
Okamoto, I. et al.; The Journal of Immunology; 162:3202-3211 (1999).
Olee, T. et al.; The Journal of Immunology; 162:1096-1100 (1999).
Pan, G. et al.; Cytokine, 13(1):1-7 (2001).
Pizarro, T.T. et al.; The Journal of Immunology; 162:6829-6835 (1999).
Puren, A.J. et al.; PNAS, 96:2256-2261 (1999).
Raeburn, C.D. et al.; Am. J. Physiol. Heart Circ. Physiol.; 283:H650-H657 (2002).
Saha, N. et al.; Arthritis & Rheumatism; 42(8):1577-1587 (1999).
Smith, D.E. et al.; The Journal of Biological Chemistry; 275(2)1169-1175 (2000).
Taylor, S.L. et al.; Genomics; 79(5):726-733 (2002).
Torigoe, K. et al.; The Journal of Biological Chemistry; 272(41):25737-25742 (1997).
Urushihara, N. et al.; Journal of Pediatric Surgery; 35(3):446-449 (2000).
Vigers, G.P.A. et al.; Nature; 386:190-194 (1997).
Xiang, Y. et al.; Proc. Natl. Acad. Sci. USA; 96:11537-11542 (1999).
Yatsiv, I. et al.; Journal of Cerebral Blood Flow & Metabolism; 22:971-978 (2002).
Yu, S. et al.; Journal of Neuropathology and Experimental Neurology; 61(7):614-622 (2002).
Zecchina, G. et al.; Journal of Hematotherapy & Stem Cell Research; 10:769-776 (2001).
Bufler, et al., “A complex of the IL-1 homologue IL-1F7b and IL-18 binding protein reduces IL-18 activity,”PNAS, vol. 99, No. 21: pp. 13723-13728, Oct. 15, 2002.
Bufler Philip
Dinarello Charles A.
Kim Soo-Hyun
Ares Trading S.A.
Nixon & Peabody LLP
Woodward Cherie
LandOfFree
Method of treatment using a cytokine able to bind IL-18BP to... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method of treatment using a cytokine able to bind IL-18BP to..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of treatment using a cytokine able to bind IL-18BP to... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3822332