Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Phosphorus containing other than solely as part of an...
Patent
1993-12-27
1995-07-11
Dees, Jose G.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Phosphorus containing other than solely as part of an...
514217, 5142258, 5142262, 514252, 514255, 514274, 514296, 514322, 514325, 514326, 514397, 514400, 514460, 514471, 514648, 514651, 514654, A61K 31675, A61K 31135
Patent
active
054321689
ABSTRACT:
Prostate cancer particularly hormone-unresponsive metastatic prostate cancer, is treated by cyclophosphamide or other normally substantially inactive agent. Potentiation of the anti-cancer activity and amelioration of cyclophosphamide-associated toxicity is achieved by an initial intravenous infusion of DPPE over an approximately one hour period prior to cyclophosphamide treatment.
REFERENCES:
patent: 4829068 (1989-05-01), Brandes et al.
patent: 4990538 (1991-02-01), Harris et al.
patent: 5130303 (1992-07-01), Akiyama et al.
Brandes et al., J. Natl. Canc. Inst., 83 (18), pp. 1329-1336 (Feb. 1991).
D. C. Smith et al., Proc. of Asco vol. 11, Mar. 1992, 666, p. 213 "High-Dose Cyclophosphamide with Granulocyte-Macrophage-Colony Stimulating Factor in Hormone-Refractory Prostatic Carcinoma".
Eisenberger et al., J. Clin. Onco., vol. 3, No. 6, Jun. 1985, pp. 827-841 "A Reevaluation of Nonhormonal Cytotoxic Chemotherapy in the Treatment of Prostatic Carcinoma".
Hsieh et al., Cancer Treatment Reviews (Sep. 1993), 19. 229-260 "Systemic therapy of prostate cancer. New concepts from prostate cancer tumor biology".
Dees Jos,e G.
Frazier Barbara S.
University of Manitoba
LandOfFree
Method of treatment of hormone-unresponsive metastatic prostate does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method of treatment of hormone-unresponsive metastatic prostate , we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of treatment of hormone-unresponsive metastatic prostate will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-503548