Method of treatment of Heliobacter pylori infections with triclo

Details Method of treatment of Heliobacter pylori infections with triclo Method of treatment of Heliobacter pylori infections with triclo

1991-04-30

1994-02-15

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Capsules

424464, 424465, 424457, 424466, 424494, 424496, 424497, A61K 958, A61K 960, A61K 962, A61K 928

Patent

active

052864928

ABSTRACT:
A method for the treatment of gastrointestinal disorders associated with Helicobacter pylori infections which comprises administering to a patient an orally effective amount of triclosan is disclosed. The triclosan may be administered in the form of powders, granules, spheroids or liquids, or in unit dosage form as capsules or tablets containing 1 to 100 mg, preferably 10 to 60 mg, of triclosan. The triclosan may also be administered in gastric sustained release medicaments either as raft forming tablets or liquids, optionally to be co-administered with a solid pharmaceutically acceptable carboxylic acid or acid salt, or as mucoadherent-coated granules or spheroids.

REFERENCES:
Patent Abstracts of Japan, vol. 14, No. 126, Mar. 9, 1990.
Rauws et al., Gastroenterology, 1988, 94:33-40.
Vaira et al., Current Opinion in Gastroenterology, 1989, 5:817-823.
McNulty et al., Antimicrobial Agents and Chemotherapy, Dec. 1985, 28,6,837-838.

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