Method of treatment for interestitial cystitis

Details Method of treatment for interestitial cystitis Method of treatment for interestitial cystitis

1988-11-01

1989-10-31

Rose, Shep K.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

A61K 31485

Patent

active

048777919

ABSTRACT:
A method of treating patients suffering from interstitial cystitis comprises daily administration to such patients of from about 1 to about 50 mg of the narcotic antagonists nalmefene or naltrexone. The nalmefene or naltrexone may be administered in equally divided doses from one to four times daily, preferably by the oral route. Parenteral administration may be utilized where suitable.

REFERENCES:
Goldstein et al., Ann. Int. Med., 98:30-34 (1983).
Simmons et al., Am. Surg., 24:664-667 (1958).
Smith et al., Arch. Path., 93:76-81 (1972).
Parivar et al., Brit. J. Urol., 58:239-244 (1986).
Tomson et al., Lancet, Nov. 2, 1985, 1010-1011.
Parsons, Urology, 29 (supplement):14-16 (1987).
Feltis et al., J. Urol., 138: 42-43 (1987).
Casale et al., J. Aller, Clin. Immunol., 73:775-781 (1984).

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