Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1988-07-22
1989-11-14
Schenkman, Leonard
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
A61K 3144
Patent
active
048808130
ABSTRACT:
A method of treating patients suffering from allergic rhinitis comprises the topical administration to the nasal passages of such patients of a liquid solution containing from about 0.5 to about 10% by weight of the narcotic antagonist nalmefene or a pharmaceutically acceptable salt thereof. The solution may be administered in spray form from a squeeze bottle or from a dropper. Administration of from about 10 to about 200 microliters of the solution into each nostril may be repeated from 1 to 5 times daily.
REFERENCES:
patent: 4454142 (1984-06-01), Tuttle
Austen, Harrison's Principles of Internal Medicine (8th ed.--McGraw Hill, New York), pp. 391-396, (1977).
Hirsch, 1984 Conn's Current Therapy, (W. B. Saunders Co., Philadelphia), pp. 585-589.
Douglas, Goodman and Gilman's The Pharmacological Basis of Therepeutics, (7th ed.--Macmillan, New York), pp. 611-613, (1985).
Casale et al., J. Aller. Clin. Immunol., 73:775-781, (1984).
Baker Cummins Pharmaceuticals, Inc.
Schenkman Leonard
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