Method of treatment

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

Reexamination Certificate

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Details

C435S377000

Reexamination Certificate

active

07341997

ABSTRACT:
The present invention relates generally to a method of treatment and in particular a method of treating disorders of the nervous system such as arising from or during disease or injury. The method of the present invention involves manipulating expression of Eph receptors or their functional equivalents to increase or decrease expression or function depending on the condition being treated.

REFERENCES:
Martone et al., Brain research, (Oct. 17, 1997) vol. 771, No. 2, pp. 238-250.
Goldshmit et al., “Axonal Regeneration and Lack of Astrocytic Gliosis in EphA4-Deficient Mice,”The Journal of Neuroscience, 24(45): 10064-10073, Nov. 10, 2004.
Dottori, et al. “EphA4 (Sek1) receptor tyrosine kinase is required for the development of the corticospinal tract”,Proc. Natl. Acad. Sci. USA, vol. 95, pp. 13248-13253, Oct. 1998.
Zhou, “The Eph Family Receptors and Ligands”,Pharmacol Ther., vol. 77, No. 3, pp. 151-181, 1998.

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