Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...
Patent
1986-12-02
1988-04-05
Meyers, Albert T.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Radical -xh acid, or anhydride, acid halide or salt thereof...
A61K 31195
Patent
active
047359684
ABSTRACT:
Tinnitus symptoms are treated with aminooxyacetic acid (AOAA) administered orally at dosages of 200-300 mg/day. Clinically significant reductions in tinnitus symptoms were observed.
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Hazell: Measurement of Tinnitus in Humans in Evered and Lawrence (eds.), Tinnitus, London, England, Pitman Books, 1981, pp. 35-53.
Tibbles JAR, McGreal DA: Trial of Amino-Oxyacetic Acid, an Anticonvulsant, Can. Med. Ass. J. 1963; 88: 881-886.
LaVeck et al.: Anticonvulsant Properties of Amino-Oxyacetic Properties of Amino-Oxyacetic Acid, J. New Drugs 1962; 2:160-166.
Bobbin et al.: Effects of Amino-Oxyacetic Acid on Cochlear Potentials and Preyer Reflex, Nature (Lond.) 1969; 223: 70-71.
Melding et al.: The Use of Intravenous Lidocaine in the Diagnosis and Treatment of Tinnitus, J. Laryngol Otol. 1978: 92: 115-121.
Bobbin et al.: An Examination of an Electrochemical Mechanism for Noise-Induced Hair Cell Loss: Noise with Amino-Oxyacetic Acid (AOAA), Trans Am Acad Ophthalmol Otolaryngol 1976; 82:299-304, Transcript.
Kilcoyne John M.
Meyers Albert T.
Tulane Educational Fund
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