Method of treating tinnitus

Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acids and salts thereof

Reexamination Certificate

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Details

C562S507000, C562S512000, C514S561000, C514S568000

Reexamination Certificate

active

07138542

ABSTRACT:
The invention relates to a method of treating tinnitus by administering an alpha2delta ligand such as, for example, a compound of Formulaand pharmaceutically acceptable salts thereof, wherein R1is hydrogen or straight or branched lower alkyl, and n is an integer of from 4 to 6.

REFERENCES:
patent: 4024175 (1977-05-01), Satzinger et al.
patent: 4087544 (1978-05-01), Satzinger et al.
patent: 5563175 (1996-10-01), Silverman et al.
patent: 6316638 (2001-11-01), Bryans et al.
patent: 2002/0072533 (2002-06-01), Schrier et al.
patent: 2 342 043 (2000-04-01), None
patent: WO 98/17627 (1998-04-01), None
patent: WO 99/31057 (1999-06-01), None
patent: WO 99/31074 (1999-06-01), None
patent: WO 99/31075 (1999-06-01), None
patent: WO 99/61424 (1999-12-01), None
patent: WO 00/76958 (2000-12-01), None
patent: WO 01/28978 (2001-04-01), None
PCT International Search Report, PCT/IB03/00232.
Zapp, “Gabapentin for the treatment of tinnitus: A case report”, Database accession No. EMB-2001-077211, abstract.
Szczepaniak and Moller, Hearing Research, 97 (1996) 46-53.
Menkes and Larson, J. Neurol. Neurosurg. Psychiatry, 1998; 65:803.
Shulman et al., “Benzodiazepine receptor deficiency and tinnitus”, Database accession No. EMB-2001-049123, abstract.
Gee et al., “The Novel Anticonvulsant Drug, Gabapentin (Neurontin), Binds to the alpha2delta Subunit of a Calcium Channel”, J. Biol. Chem., 271(10):5768-5776, 1996.
C. A. Bauer, et al., “Assessing Tinnitus and Prospective Tinnitus Therapeutics Using a Psychophysical Animal Model”, Journal of the Association for Research in Otalaryngolgy, 2001, 2/1:054-064.
N. S. Gee et al., “The Novel Anticonvulsant Drug, Gabapentin (Neurontin), Bi9nds to the alpha2delta Subunit of a Calcium Channel”, Journal of Biological Chemistry, 1996, 271, 5879-5776.

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