Method of treating skin diseases

Details Method of treating skin diseases Method of treating skin diseases

1981-05-06

1990-09-04

Killos, Paul J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ester doai

514560, 514627, 514675, 514886, 2604109R, 2604109V, 260404, 260413, A01N 3702, C07C 5703

Patent

active

049545256

ABSTRACT:
Skin diseases with keratinization and allergic or inflammatory skin diseases are treated by orally or parenterally administering to an adult human patient from 40 mg to 4 g/day of a polyprenyl compound having the formula (I): ##STR1## in which each of n and m is 0, 1, or 2, n+m is 0, 1 or 2, A is ##STR2## and B is ##STR3## [in which R represents the hydroxyl group, a lower alkoxy group, or ##STR4## (wherein each of R.sub.1 and R.sub.2 is the hydrogen atom, a lower alkyl group or an aryl group)]; provided that R is a lower alkoxy or ##STR5## if n is 1, m is 0, a is ##STR6## and B is ##STR7##

REFERENCES:
patent: 4147708 (1979-04-01), Manchand
patent: 4346109 (1982-08-01), Yamatsu et al.
patent: 4490414 (1984-12-01), Dawson
patent: 4722939 (1988-02-01), Loev
Caliezi et al, Helv. Chim. Acta, vol. 35, pp. 1649-1655, (1952).
Agri. Biol. Chem., vol. 34, No. 8, p. 1184, (1970).
Journal Chem. Soc., (London), (C), pp. 2154-2165, (Davis et al.).

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