Drug – bio-affecting and body treating compositions – Conjugate or complex of monoclonal or polyclonal antibody,... – Conjugated via claimed linking group – bond – chelating agent,...
Patent
1978-04-12
1979-10-30
Brown, Johnnie R.
Drug, bio-affecting and body treating compositions
Conjugate or complex of monoclonal or polyclonal antibody,...
Conjugated via claimed linking group, bond, chelating agent,...
536 23, A61K 3170, C07H 1908
Patent
active
041728890
ABSTRACT:
A process of treatment for the management of the condition known as rheumatoid arthritis. The process manages rheumatoid arthritis by controlling the inflammatory process in a rheumatoid joint by the intra-articular administration to said joint of an effective amount for controlling the inflammatory process of certain N.sup.4 -acyl-ara-cytidines, 5'-O-acyl-ara-cytidines and pharmaceutically acceptable acid addition salts thereof, and pharmaceutically acceptable acid addition salts of 5'-O-acyl-2,2'-anhydro-ara-cytidines.
REFERENCES:
patent: 3894000 (1975-07-01), Wechter et al.
patent: 3920630 (1975-11-01), Wechter et al.
Glenn, E. Myles, "Proc. Soc. Exptl. Biol. and Med.", 129, pp. 860-864, 1968.
Gray et al., "Biochemical Pharmacology", vol. 21, pp. 465-475, Pergamon Press, 1972, Great Britain.
Wechter et al., "Jour. of Medicinal Chem.", vol. 18, No. 4, 1975, pp. 339-344.
Brooks Carter D.
Wechter William J.
Brown Johnnie R.
Jameson William G.
The Upjohn Company
Williams, Jr. Sidney B.
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