Method of treating pulmonary inflammation

Details Method of treating pulmonary inflammation Method of treating pulmonary inflammation

1991-02-22

1992-01-14

Goldberg, Jerome D.

Drug, bio-affecting and body treating compositions

Fermentate of unknown chemical structure

Having a known elemental analysis

514291, A61K 3574, A61K 3144

Patent

active

050808990

ABSTRACT:
This invention provides a method of preventing or reversing pulmonary inflammation in a mammal by administering an effective amount of rapamycin orally, parenterally, intranasally, or intrabronchially. As such, rapamycin is useful in providing the symptomatic relief of diseases in which pulmonary inflammation is a component such as, asthma, chronic obstructive pulmonary disease, emphysema, acute respiratory distress syndrome, bronchitis, and the like.

REFERENCES:
patent: 3929992 (1975-12-01), Sehgal et al.
Abstract of Areugi (Jap. J. Allergology) 39(5):483 (1990).
Am. Rev. Resp. Dis. 131:373 (1985).
J. Allergy Clin. Immunol. 85:533 (1990).
Am. Rev. Resp. Dis. 140:225 (1989).
J. Immunol. 141:4158 (1988).
Can. J. Physiol. Pharmacol. 55, 48 (1977).
FASEB 3,3411 (1989).
Med. Sci. Res. 17:877 (1989).
Chemical Abstracts 87:111825p (1977).

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