Method of treating peripheral vasoconstriction with tamoxifen ci

Details Method of treating peripheral vasoconstriction with tamoxifen ci Method of treating peripheral vasoconstriction with tamoxifen ci

1994-05-23

1995-11-28

Fay, Zohreh

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Nitrogen containing other than solely as a nitrogen in an...

514653, 514654, A61K 31135

Patent

active

054708834

ABSTRACT:
A method of modifying peripheral vasoconstriction comprising administering a pharmacologically acceptable dose of tamoxifen.

REFERENCES:
NOVADEX (Tamoxifen Citrate) package insert, Zeneca Pharmaceuticals, Wilmington, Del.; Aug. 1993.
Schrijver, J. et al., Investigations on the Nutritional Status of Advanced Breast Cancer Patients. The Influence of Long-Term Treatment with Megestrol Acetate of Tamoxifen; Nutrition and Cancer, vol. 10, No. 4 1987 pp. 231-245.
Lipton, A., The anti-oestrogen tamoxifen is a calcium antagonist in perfused rat mesentery; Cancer Chemotherapy and Pharmacology; (1987) 20:125-127.
Kocsis, J. et al., Effect if the anti-oestrogen Tamoxifen on the development of renal cortical necrosis induced by oestrone+vasopressin administered in rats; Br. J. Exp. Path. (1988), 157-168.
Etgen, A. and Petitti, N., Mediation of Norepinephrine-Simulated Cyclic AMP Acumulation by Adrenergic Receptors in Hypothalmic and Preoptic Area Slices: Effects of Estradiol, Journal of Neurochemistry, vol. 49, No. 6, 1987, pp. 1732-1739.
Baksi, S. et al. Antiestrogen-Induced Alterations of Hypothalmic Dopamine and Norepinephrine Levels in the Female Rat, Neuropharmacology, vol. 20, 1981, pp. 1163-1167.

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