Method of treating osteoporosis with 1 .alpha.25-dihydroxy-22(E)

Details Method of treating osteoporosis with 1 .alpha.25-dihydroxy-22(E) Method of treating osteoporosis with 1 .alpha.25-dihydroxy-22(E)

1993-10-25

1995-02-28

Henley, III, Raymond J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

9,10-seco- cyclopentanohydrophenanthrene ring system doai

514168, 552653, A61K 3159, A61K 31595

Patent

active

053937490

ABSTRACT:
A method of treating osteoporosis comprising the administration of an effective amount of 1.alpha.,25-dihydroxy-22(E)-dehydro-vitamin D.sub.3.

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J. Nutr. Biochem., vol. No. 1, Jan. 1993, pp. 49-57, Tai C. Chen et al, "An Evaluation of 1,25-Dihydroxyvitamin D.sub.3 Analogues on the Proliferation and Differentiation of Cultured Human Keratinocytes, Calcium Metabolism and the Differentiation of Human HL-60 Cells".
Arch. Toxicol, vol. 63, No. 5, 1989, pp. 394-400, Andreas Istler et al, "Effects of vitamin D Derivatives on Soft Tissue Calcification in Neonatal and Calcium Mobilization in Adult Rats".

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