Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1991-11-27
1995-04-11
Schain, Howard E.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
514 8, C07K 1528, C12N 512, G01N 3353
Patent
active
054058325
ABSTRACT:
A method of treating non-Streptococcal bacterial infections in a mammal comprising administering to the mammal an effective amount of modified C-reactive protein (CRP) in a pharmaceutically-acceptable carrier. Modified-CRP has been found to be particularly effective in treating gram-negative bacterial infections and endotoxic shock.
REFERENCES:
patent: 5272258 (1993-12-01), Siegel et al.
Ballou et al., J. Lab. Clin. Med., 115, 332-338 (1990).
Barna et al., Cancer Research, 44, 305-310 (1984).
Bray et al., Clin. Immunol. Newsletter, 8, 137-140 (1987).
Chu et al., Proc. Amer. Acad. Cancer Res., 28, 344a (1987).
Chu et al., Proc. Amer. Acad. Cancer Res., 29, 371a (1988).
Chudwin et al., J. Allergy Clin. Immunol., 77, 216a (1986).
Deodhar et al., Cancer Research, 42, 5084-5088 (1982).
Galanos et al., Proc. Natl. Acad. Sci. USA, 76, 5939 (1979).
Gotschlich, Ann. N.Y. Acad. Sci., 557, 9-18 (1989).
Gupta et al., J. Immunol., 137, 2173-2179 (1986).
Hokama et al., J. Bacteriology, 83, 1017-1024 (1962).
Horowitz et al., J. Immunol., 138, 2598-2603 (1987).
Hu et al., J. Biol. Chem., 263, 1500-1504 (1988).
Hu et al., Biochem., 25, 7834-7839 (1986).
James et al., Dissertation Abstracts International, 41/08-B, 2963 (1980).
Kempka et al., J. Immunol., 144, 1004-1009 (1990).
Kilpatrick and Volanakis, Immunol. Res., 10, 43-53 (1991).
Kilpatrick and Volanakis, J. Immunol., 134, 3364-3370 (1985).
Kindmark, Clin. Exp. Immunol., 8, 941-948 (1971).
Lei et al., J. Biol. Chem., 260, 13377-13383 (1985).
Mantzouranis et al., Ped. Res., 18, 260a (1984).
Mitzner et al., Artificial Organ, 15, 338 (1991).
Mold et al., Ann. N.Y. Acad. Sci., 389, 251-262 (1982).
Mold et al., Infection and Immunity, 38, 392-395 (1982).
Nagaki et al., Artificial Organ, 15, 338 (1991).
Nakayama et al., Clin. Exp. Immunol., 54, 319-326 (1983).
Nakayama et al., J. Immunol., 132, 1336-1340 (1984).
Nanbu et al., Artificial Organ, 15, 290 (1991).
Noronha-Blob et al., Eur. J. Pharmacol., 199, 387-388 (1991).
Potempa et al., Protides Biol. Fluids, 34, 287-290 (1986).
Potempa et al., Mol. Immunol., 24, 531-541 (1987).
Potempa et al., Inflammation, 12, 391-405 (1988).
Potempa et al., Mol. Immunol., 20, 1165-1175 (1983).
Potempa et al., FASEB J., 2, 731a (1988).
Potempa et al., Proc. Amer. Acad. Cancer Res., 28, 344a (1987).
Rees et al., Fed. Proc., 45, 263a (1986).
Samols et al., Biochem. J., 227, 759-765 (1985).
Samola and Hu, Protides Biol. Fluids, 34, 263-266 (1986).
Tebo et al., J. Immunol., 144, 231-238 (1990).
Teng et al., Proc. Natl. Acad. Sci. USA, 82, 1790-1794 (1985).
Thombre et al., Cancer Immunol. Immunother., 16, 145-150 (1984).
Tillett and Francis, J. Exp. Med., 52, 561-571 (1930).
Volanakis, et al., J. Immunol., 113, 9-17 (1974).
Whitehead et al., Biochem. J., 266, 283-290 (1990).
Woo et al., J. Biol. Chem., 260, 13384-13388 (1985).
Xia et al., FASEB J., 5, A1628 (1991).
Ying et al., J. Immunol., 143, 221-228 (1989).
Zeller et al., Fed. Proc., 46, 1033a (1987).
Ziegler et al., New Eng. J. Med., 324, 429-435 (1991).
Ziegler et al., Clin. Res., 35, 619A (1987).
Bacterial Endotoxic Lipopolysaccharides, vol. II, Immunopharmacology as Pathophysiology, ed by J. L. Ryan ad D. C. Morrison, CRC Press, Boca Raton.
F. B. Taylor, Jr., Baboon Model of E. Coli Seplsis: Summary . . . Marbers, #42, Collogiom, Mosbach '91 Molecular Aspects of Inflammation, Springer-Verlag, Berlin, 1991.
Ammar et al. J. Clin. Invest., 87(6) 2048-2055 Biological and Biochemical . . . normal T Cells.
Rudd et al, PNAS, 85 pp. 5190-5194 Jul. '88, The C04 Receptor . . . T lymphocytes.
Immtech International Inc.
Schain Howard E.
Touzeau Phynn
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