Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1991-08-09
1992-09-29
Bond, Robert T.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
548950, 546275, A61K 31395, C07D20504
Patent
active
051514184
ABSTRACT:
A method of treating animals to obtain muscle relaxation and/or to relieve anxiety is disclosed utilizing novel and known 3-aryloxy and 3-arylthioazetidinecarboxamides having the formula: ##STR1## wherein Z is oxygen or sulfur; B is oxygen or sulfur; Ar is pyridyl or halo substituted pyridyl, phenyl or substituted phenyl; R.sup.1 and R.sup.2 are hydrogen, loweralkyl, aryl, allyl groups, propargyl, cycloalkyl, loweralkylcycloalkyl, cycloalkylloweralkyl, arylloweralkyl and diloweralkylaminoalkyl, and R.sup.1 and R.sup.2 when taken together with the adjacent nitrogen atom may form a heterocyclic amine radical; R.sup.3 is hydrogen, loweralkyl, aryl or arylloweralkyl, and the geometrical isomers thereof and pharmaceutical salts thereof and hydrates thereof when they are possible.
REFERENCES:
patent: 4031221 (1977-06-01), Helsley
patent: 4226861 (1980-10-01), Cale
patent: 4547514 (1985-10-01), Mathur
patent: 4571393 (1986-02-01), Teng
patent: 4956359 (1990-09-01), Taylor
Cale, Jr. Albert D.
Johnson David N.
Stauffer, Jr. Harold F.
Taylor, Jr. Chandler R.
A. H. Robins Company Incorporated
Bond Robert T.
Boswell, Jr. Robert F.
Ward E. C.
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