Drug – bio-affecting and body treating compositions – Extract – body fluid – or cellular material of undetermined... – Body fluid or exudate or transudate other than snake venom,...
Reexamination Certificate
2007-05-29
2007-05-29
Davis, Ruth A (Department: 1651)
Drug, bio-affecting and body treating compositions
Extract, body fluid, or cellular material of undetermined...
Body fluid or exudate or transudate other than snake venom,...
C424S520000, C424S548000, C424S400000
Reexamination Certificate
active
10727893
ABSTRACT:
Disclosed is a product and method for transplanting biological fluids into a host animal (including humans) that have been collected from donor animals. These biological fluids have been purified and processed so that they are a cellular, sterile, pathogen free, and a form that can be stored for considerable periods of time without degradation. In one embodiment, synovial fluid is harvested from a large number of donors to produce the transplantation compound. Donor fluid is collected from a number of joints per animal, and initially screened for obvious abnormalities (clarity, color, viscosity . . . etc.) and accepted or rejected on a joint-by-joint basis at the time of collection. The collected fluid is frozen in the field. Once in a laboratory setting, the fluid is warmed and spun down in a centrifuge. The supernate is collected, filtered, and mixed in large batches while the permeate is discarded. The supernate is re-frozen, lyophilized (freeze-dried) to form a cake and packaged as an individual dose under vacuum. The product is sterile, stable, has a long shelf life and can be readily reconstituted and injected into a joint.
REFERENCES:
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Rulcker, C. and Lindholm, A. Preliminary trial of synovial fluid transfer for treating joint lameness in Standardbreds, Equine Vet. Journal. vol. 13 No. 4, (1981) pp. 264-266.
Christofferson Paul V.
Meader Charles P.
Cochran Freund & Young LLC
Davis Ruth A
Equine Bio-Tech, Inc.
Thompson Paul M.
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