Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1982-03-09
1983-07-05
Roberts, Elbert L.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
A01N 4500, A61K 3159
Patent
active
043918026
ABSTRACT:
A method of leukemia or leukemoid disease treatment by administration of a vitamin D derivative with a hydroxyl group at 1.alpha.-position is disclosed. It is believed that the vitamin D derivative with a hydroxyl group at 1.alpha.-position is capable of treating cancer through redifferentiation of cancer cells and that this capability is inherent in vitamin D derivatives with a hydroxyl group at 1.alpha.-position.
REFERENCES:
patent: 4263214 (1981-04-01), De Luca et al.
Chemical Abstracts, 90, 133429b (1979).
Chemical Abstracts, 83, 53688a (1975).
Chemical Abstracts, 88, 69462m (1978).
Weiss, B. et al., "Indirect induction of differentiation in myeloid leukemic cells by lipid A" Proc. Natl. Acad. Sci. USA, vol. 75, No. 3, pp. 1374-1378 (1978).
Abe Etsuko
Aoki Tadao
Hirasawa Yoshihei
Konno Kunio
Suda Tatsuo
Chugai Seiyaku Kabushiki Kaisha
Roberts Elbert L.
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