Drug – bio-affecting and body treating compositions – Lymphokine – Interferon
Patent
1987-05-18
1990-05-29
Hazel, Blondel
Drug, bio-affecting and body treating compositions
Lymphokine
Interferon
435 704, 435 705, A61K 4502, C12P 2100
Patent
active
049294431
ABSTRACT:
Methods and means for treating interferon-sensitive diseases are disclosed, wherein a whole blood sample is taken from a patient suffering from such disease and is incubated in vitro together with a mitogen to produce .gamma.-interferon. After incubation the whole blood sample is subjected to a separation step for producing a blood plasma product, which is free from the mitogen but contains .gamma.-interferon. This blood plasma product is used for re-administration to the patient from which the whole blood sample was taken.
REFERENCES:
patent: 4382027 (1983-03-01), Braude
patent: 4490357 (1984-12-01), Skurkovich et al.
Skurkovich, et al., Bomedicine, vol. 29, pp. 227-228, 1978.
O'Malley, J.; Methods in Enzymology, vol. 78, pp. 540-545, Academic Press, 1981.
Osther, K., et al., The Biology of the Interferon System E. De Maeyes and H. Schellekens, ed., pp. 527-533, 1963.
Lindblom Ragnvald E.
Rothman Ulf S.
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