Method of treating inflammation with cartilage inducing factor

Details Method of treating inflammation with cartilage inducing factor Method of treating inflammation with cartilage inducing factor

1988-10-27

1990-11-20

Stone, Jacqueline

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 2, 530324, A61K 3702, C07K 710

Patent

active

049719521

ABSTRACT:
Inflammation, acute and/or chronic, is treated with a CIF (TGF-beta). The CIF may be administered locally or systemically, depending upon the indication, and does not require coadministration of activator or cofactor for efficacy.

REFERENCES:
patent: 4473551 (1984-09-01), Schinitsky
Shipley et al., (1985) Proc. Natl. Acad. Sci. USA 82:4147-4151.
Moses, (1985) Fed. Proc. 44(3), VIII abstract.
Kehrl et al., (1985) Clinical Research 33(2):610A.
Brinckerhoff, (1983) Arthritis and Rheumatism 26(11):1370-1379.
Tashjian et al., (1985) Proc. Natl. Acad. Sci. USA 82:4545-4538.
Roberts et al., (1985) Proc. Natl. Acad. Sci. USA 82:119-123.
Baserga, (1981) Handbook of Experimental Pharmacology 57:385-404.

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