Method of treating inflammation using soluble IL-17RCX4

Details Method of treating inflammation using soluble IL-17RCX4 Method of treating inflammation using soluble IL-17RCX4

2007-02-09

2009-11-24

Landsman, Robert (Department: 1647)

Drug, bio-affecting and body treating compositions

Immunoglobulin, antiserum, antibody, or antibody fragment,...

Monoclonal antibody or fragment thereof

C514S012200, C530S350000, C530S388300, C530S391100

Reexamination Certificate

active

07622116

ABSTRACT:
The present invention relates to blocking, inhibiting, reducing, antagonizing or neutralizing the activity of IL-17F, IL-17A, or both IL-17A and IL-17F polypeptide molecules. IL-17A and IL-17F are cytokines that are involved in inflammatory processes and human disease. IL-17RC is a common receptor for IL-17A and IL-17F. The present invention includes methods of using a soluble IL-17RC receptor, IL-17RCx4 for treating inflammation.

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